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Infiltrative Basal Cell Carcinoma: A Nonsclerosing Subtype

SIEGLE, RONALD J. M.D.¹; MacMILLAN, JULIE M.P.H.²; POLLACK, SHELDON V. M.D.²

¹ Ronald J. Siegle, M.D., is Assistant Professor of Medicine, Division of Dermatology, The Ohio State University, Columbus, Ohio.

² Julie MacMillan, M.P.H., Research Associate, Duke Comprehensive Cancer Center, and Sheldon V. Pollack, M.D., Chief, Mohs Surgery and Dermatologic Surgery Unit, Division of Dermatology, are from the Duke University Medical Center, Durham, North Carolina.

Address reprint requests to Ronald J. Siegle, M.D., Ohio State University, 4731 UHC, 456 Clinic Drive, Columbus, OH 43210–1228.

This work was completed in the Mohs Surgery Unit, Division of Dermatology, Duke University Medical Center.

The Journal of Dermatologic Surgery and Oncology 12(8):p 830-836, August 1986. | DOI: 10.1111/j.1524-4725.1986.tb01990.x

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Abstract

Infiltrative basal cell carcinoma is a distinct histologic subtype of basal cell carcinoma (BCC). Criteria for its diagnosis are presented and its nonsclerotic nature emphasized. Analysis of 174 consecutive BCCs referred for Mohs micrographic surgery showed the infiltrative subtype (29 tumors) to be significantly more destructive and difficult to treat than the more common nodular BCC.