Acetophenone azine (AA) has recently been identified as a new allergen in shin pads and sports shoes. We report the case of a boy with allergic contact dermatitis of the shins caused by AA present in his shin pads. High-performance liquid chromatography of samples of shin pads was performed to help identify potential contact allergens. Patch tests revealed strongly positive reactions to pieces of his shin pads and to AA down to a concentration of 0.001% in acetone. To our knowledge, this is the first reported case of allergic contact dermatitis to AA in the United Kingdom. Here we recommend the optimal concentration of AA for patch testing at 0.1% in acetone and summarize previous relevant published cases.
From the *Department of Dermatology, Royal Free London NHS Foundation TRUST, London, United Kingdom; and
†Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
Address reprint requests to Dimitra Koumaki, MD, MSc, PhD, Dermatology Department, Royal Free London NHS Foundation TRUST, Pond St, Hampstead, London NW3 2QG, United Kingdom. E-mail: firstname.lastname@example.org.
The authors have no funding or conflicts of interest to declare.
Informed consent was obtained from the mother of the child for publication of his images.
This manuscript contains original unpublished work and is not being submitted for publication elsewhere at the same time.