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Allergic Contact Dermatitis to Ophthalmic Medications: Relevant Allergens and Alternative Testing Methods

Grey, Katherine R. BA; Warshaw, Erin M. MD, MS

doi: 10.1097/DER.0000000000000224
Reviews

Allergic contact dermatitis is an important cause of periorbital dermatitis. Topical ophthalmic agents are relevant sensitizers. Contact dermatitis to ophthalmic medications can be challenging to diagnose and manage given the numerous possible offending agents, including both active and inactive ingredients. Furthermore, a substantial body of literature reports false-negative patch test results to ophthalmic agents. Subsequently, numerous alternative testing methods have been described. This review outlines the periorbital manifestations, causative agents, and alternative testing methods of allergic contact dermatitis to ophthalmic medications.

From the *University of Minnesota Medical School; †HCMC Parkside Occupational and Contact Dermatitis Clinic; ‡Department of Dermatology, Minneapolis Veterans Affairs Medical Center; and §Department of Dermatology, University of Minnesota Medical School, Minneapolis.

Corresponding author: Katherine Grey, Department of Dermatology, Minneapolis Veterans Affairs Medical Center, 111K 1 Veterans Drive, Minneapolis, MN 55417. E-mail: greyx013@umn.edu.

No reprints available.

The authors have no funding or conflicts of interest to declare.

This material is based on work, supported in part, by the Minneapolis Veterans Affairs Medical Center. The contents of this publication do not represent the views of the Department of Veterans Affairs or the US Government.

© 2016 American Contact Dermatitis Society
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