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Recommendations for a Screening Series for Allergic Contact Eyelid Dermatitis

Herro, Elise M. MD*; Elsaie, Mohammed L. MD; Nijhawan, Rajiv I. MD; Jacob, Sharon E. MD*

doi: 10.1097/DER.0b013e31823d191f

Background Although allergic contact dermatitis of the eyelids is a common condition, limited information is available regarding the selection of patch-testing chemicals for proper evaluation.

Objective The purpose of this analysis was to evaluate the relevance of allergens responsible for allergic eyelid dermatitis among a series of patch-tested patients attending our clinic at the University of Miami and compare these results to published studies in the literature.

Methods Data were retrospectively reviewed for eyelid-only dermatitis from clinically relevant patch-test evaluations performed between December 2004 and January 2007.

Results Formaldehyde was the most frequently encountered antigen, accounting for 45.83% (11/24) of the cases, followed by nickel 33.33% (8/24) and balsam of Peru (Myroxylon pereirae) 29.17% (7/24). In addition, not only did we find a higher prevalence of certain allergens when compared with other studies, but we identified several relevant allergens not previously reported at other referral centers.

Conclusions The allergens found to be relevant in eyelid dermatitis vary among different regions. These data may help contribute to generating a standard screening tool to improve the detection and management of these cases.

From the *Division of Dermatology, University of California, San Diego, and Rady Children’s Hospital, San Diego, CA; †National Research Centre, Egypt and Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL; and ‡Department of Dermatology, Roosevelt University, New York, NY.

Address reprint requests to Sharon E. Jacob, MD, Rady Children’s Hospital, 8010 Frost St, Suite 602, San Diego, CA 92123. E-mail:

The authors have no funding or conflicts of interest to declare.

©2012American Contact Dermatitis Society, All Right Reserved
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