November 2019 - Volume 62 - Issue 11 : Diseases of the Colon & Rectum

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November 2019 - Volume 62 - Issue 11
pp: 1269-1408,e440-e450

Perianal Neoplasia

Colorectal Cancer

Age at Diagnosis and Sex Are Associated With Long-term Deficits in Disease-Specific Health-Related Quality of Life of Survivors of Colon and Rectal Cancer: A Population-Based Study

Thong, Melissa S.Y.; Doege, Daniela; Koch-Gallenkamp, Lena; More

Diseases of the Colon & Rectum. 62(11):1294-1304, November 2019.

Implementation of an Enhanced Recovery Protocol Is Associated With On-Time Initiation of Adjuvant Chemotherapy in Colorectal Cancer

Hassinger, Taryn E.; Mehaffey, J. Hunter; Martin, Allison N.; More

Diseases of the Colon & Rectum. 62(11):1305-1315, November 2019.

Differential Survival Benefits of 5-Fluorouracil–Based Adjuvant Chemotherapy for Patients With Microsatellite-Stable Stage III Colorectal Cancer According to the Tumor Budding Status: A Retrospective Analysis

Yamadera, Masato; Shinto, Eiji; Kajiwara, Yoshiki; More

Diseases of the Colon & Rectum. 62(11):1316-1325, November 2019.

Inflammatory Bowel Disease

Exposure to Anti-tumor Necrosis Factor Medications Increases the Incidence of Pouchitis After Restorative Proctocolectomy in Patients With Ulcerative Colitis

Bertucci Zoccali, Marco; Hyman, Neil H.; Skowron, Kinga B.; More

Diseases of the Colon & Rectum. 62(11):1344-1351, November 2019.


Postoperative Outcomes of Patients With Nonperforated Gangrenous Appendicitis: A National Multicenter Prospective Cohort Analysis

de Wijkerslooth, Elisabeth M.L.; de Jonge, Joske; van den Boom, Anne Loes; More

Diseases of the Colon & Rectum. 62(11):1363-1370, November 2019.


Spanish Abstract Translations

Creator: Maude Trepanier, et al.
Duration: 3:08
Editor Pick 5, Video Abstract, November 2019 Issue.
CONCLUSIONS: Despite the rarity of venous thromboembolic events, extended thromboprophylaxisis a cost-effective strategy.
Creator: Ira L. Leeds et al.
Duration: 2:25
Editor Pick 4, Video Abstract, November 2019 Issue.
CONCLUSION: Extended prophylaxis in patients with Crohn’s disease postoperatively is not cost-effective whenthe cumulative incidence of posthospital thrombosis remains less than 4.9%. These findings are driven by the low absolute risk of thrombosis in this population and the considerable cost of universal treatment.
Creator: Marco Bertucci Zoccali, et al.
Duration: 2:31
Editor Pick 3, Video Abstract, November 2019 Issue.
CONCLUSION: In a large cohort of patients undergoing IPAA for ulcerative colitis with at least a 5-year follow-up, anti-tumor necrosis factor exposure was the only independent risk factor for the development of pouchitis. These agents may “precondition” the pouch to develop pouchitis through alterations in the microbiome and/or local host immunity of the terminal ileum.
Creator: Taryn E. Hassinger, et al.
Duration: 2:57
Editor Pick 2, Video Abstract, November 2019 Issue.
CONCLUSIONS: Enhanced recovery was associated with receiving on-time adjuvant chemotherapy. As promptinitiation of adjuvant chemotherapy improves survival in colorectal cancer, future investigation of long-term oncologic outcomes is necessary to evaluate the potential impact of enhanced recovery on survival.
Creator: Melissa S.Y. Thong, et al.
Duration: 5:03
Editor Pick 1, Video Abstract, November 2019 Issue
Our results suggest that supportive care for survivors of colon and rectal cancer to improvetheir self-management of symptoms should be adapted according to cancer type, age at diagnosis, and sex.