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Visceral Fat and Anastomotic Leakage After Colon Cancer Resection

Video Author: Wouter M. Verduin, M.D. • Anne-Loes K. Warps, M.D. • Rick van den Helder, M.D. • Hieronymus J. Doodeman, MSc. • Alexander P.J. Houdijk, M.D., Ph.D., on behalf of the INfluences of Fat And MUscle in colorectal Surgery Collaborative
Published on: 01.12.2021

The independent association of visceral fat with anastomotic leakage was confined to the elective colon cancer resection group. The previously reported associations of male sex and BMI with anastomotic leakage were explained by visceral fat. Visceral fat–associated comorbidities did not influence anastomotic leakage, suggesting that its effect on colon anastomotic healing is local rather than systemic. Future risk analysis for anastomotic leakage in colon cancer surgery should contain visceral fat values and consider subgroup differences.

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