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Survival Benefit for Metformin Through Better Tumor Response by Neoadjuvant Concurrent Chemoradiotherapy in Rectal Cancer

Video Author: Jung Min Kim, M.D. • Jung Won Park, M.D. • Jin Ha Lee, M.D. • Ye Hyun Park, M.D. • Soo Jung Park, M.D., Ph.D.1 • Jae Hee Cheon, M.D., Ph.D. • Won Ho Kim, M.D.,Ph.D. • Tae Il Kim, M.D., Ph.D.
Published on: 05.18.2020

Metformin use was associated with better tumor responses and cancer-specific survival, as well as a lower risk of cancer recurrence, in patients with diabetes mellitus who had lymph node downstaging after neoadjuvant concurrent chemoradiotherapy in rectal cancer.

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Creator: Yesenia Rojas-Khalil, MD
Duration: 10:03
Resumen de la edicion por Yesenia Rojas-Khalil, MD
Creator: Yesenia Rojas-Khalil, MD
Duration: 9:35
Resumen de la edicion por Yesenia Rojas-Khalil, MD
Creator: Jacopo Crippa, M.D. • Emilie Duchalais, M.D. • Nikolaos Machairas, M.D. • Amit Merchea, M.D.2 • Scott R. Kelley, M.D. • David W. Larson, M.D., M.B.A.
Duration: 1:35
The occurrence of anastomotic leak after restorative resection for rectal cancer did not impact long-term oncological outcomes in our cohort of patients.
Creator: Jung Min Kim, M.D. • Jung Won Park, M.D. • Jin Ha Lee, M.D. • Ye Hyun Park, M.D. • Soo Jung Park, M.D., Ph.D.1 • Jae Hee Cheon, M.D., Ph.D. • Won Ho Kim, M.D.,Ph.D. • Tae Il Kim, M.D., Ph.D.
Duration: 1:41
Metformin use was associated with better tumor responses and cancer-specific survival, as well as a lower risk of cancer recurrence, in patients with diabetes mellitus who had lymph node downstaging after neoadjuvant concurrent chemoradiotherapy in rectal cancer.
Creator: Jessica N. Cohan, M.D., M.A.S., Colleen Donahue, M.D., Haddon J. Pantel, M.D, Rocco Ricciardi, M.D., David A. Kleiman, M.D., M.Sc..,Thomas E. Read, M.D, Peter W. Marcello, M.D.
Duration: 2:41
An endoscopic step-up approach to colon polyps is associated with less morbidity, decreased healthcare costs, and colon preservation in 95% of patients. Additional studies are needed to evaluate long-term quality of life and polyp recurrence in this group.
Creator: Sergei Bedrikovetski, B.H.Sc.(Hons.), Nagendra N. Dudi-Venkata, M.B.B.S. GDipSurgicalEd, Hidde M. Kroon, M.D., Ph.D., James W. Moore, M.D., F.R.A.C.S., Ronald A. Hunter, M.B.B.S., F.R.A.C.S., Tarik Sammour, M.B.Ch.B., F.R.A.C.S., Ph.D.
Duration: 2:48
In this patient population, minimally invasive proctectomy demonstrated similar margin rates in comparison with open proctectomy, with a reduced length of stay but a higher overall complication rat
Creator: Sunil V. Patel, M.Sc., M.D. • Gary Ko, M.D.1 • Michael J. Raphael, M.D. • Christopher M. Booth, M.D.• Susan B. Brogly, M.Sc., Ph.D. • Maria Kalyvas, M.D. • Wenbin Li, M.Sc. • Timothy Hanna, Ph.D., M.D.
Duration: 1:59
In this large, contemporary cohort of patients with squamous cell carcinoma of the anus, the proportion of patients undergoing salvage surgery was considerably lower than previous reports. Younger age was associated with salvage surgery, and there was a suggestion of lower risk of salvage surgery with completion of chemoradiation. Patients requiring salvage surgery had poor 5-year overall survival.
Creator: Takeru Matsuda, M.D., Ph.D., Kimihiro Yamashita, M.D., Ph.D., Hiroshi Hasegawa, M.D., Ph.D., Akira Arimoto, M.D., Ph.D., Akihiro Watanabe, M.D., Masashi Yamamoto, M.D., Ph.D., Shingo Kanaji, M.D., Ph.D., Taro Oshikiri, M.D., Ph.D., Tetsu Nakamura, M.D.,
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Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Susan Galandiuk, MD
Duration: 10:58
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator: Brian D. Lo, B.S. • Ira L. Leeds, M.D., M.B.A., Sc.M. • Margaret H. Sundel, M.D. Susan Gearhart, M.D. • Gabriela Nisly, B.S. • Bashar Safar, M.B.B.S.Chady Atallah, M.D. • Sandy H. Fang, M.D.
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Although minimally invasive surgical approaches have decreased postoperative complications, this effect may be reversed in frail patients. These findings challenge the belief that robotic surgery provides a favorable alternative to open surgery in frail patients.
Creator: Alice M. Couwenberg, M.D. • Martijn P.W. Intven, M.D., Ph.D. • Madelijn Leoniek Gregorowitsch, M.D. • Cees Haaring, B.Sc • Wilhelmina van Grevenstein, M.D., Ph.D. • Helena MariekeVerkooijen, M.D., Ph.D.
Duration: 3:40
Patient-reported work ability deteriorates during rectal cancer treatment. Within 24 months after diagnosis, work ability returns to pretreatment level but remains lower than that of the general population.
Creator: Yuksel Altinel, M.D. • Paul M. Cavallaro, M.D. • Rocco Ricciardi, M.D., M.P.H. • Marc S. Rubin, M.D. • Ronald Bleday, M.D. • Fraz Ahmed, M.D., M.P.H • .Liliana Bordeianou, M.D., M.P.H.
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Patients undergoing elective surgery for complex diverticulitis did not have more episodes.Instead, complex diverticulitis may be a reflection of a complicated patient, suggesting that complicated patients should have a different algorithm of care at the time of their initial presentation with diverticulitis to prevent the development of complex disease.
Creator: Britt J.P. Hupkens, M.D. • Stéphanie O. Breukink, M.D., Ph.D. • Jan H.M.B. Stoot, M.D., Ph.D. • Renee E Toebes, B.Sc.• Marit E. van der Sande, M.D. • Jarno Melenhorst, M.D., Ph.D. • Geerard L. Beets, M.D., Ph.D. • Carmen D. Dirksen, M.Sc., Ph.D
Duration: 3:24
Overall survival was good in both subgroups and comparable to literature. The mean costs per patient differ between the watch-and-wait subgroup (€6713) and the total mesorectal excision subgroup (€17,108). No comparison between the groups could be made. Based on the results of this study, the current strategy, where patients with a clinical complete response are treated in a watch-and-wait policy, and patients with an incomplete response are treated with total mesorectal excision, is likely to be (cost)saving.
Creator: Rebecca G. Rogers, M.D. • Vivian W. Sung, M.D. • Emily S. Lukacz, M.D. • Pamela Fairchild, M.D. • Lily A. Arya, M.D. • Matthew D. Barber, M.D., M.H.S. • D. Markland, M.D. • Nazema Y. Siddiqui, M.D. • Carla M. Bann, Ph.D. on behalf of the National Insti
Duration: 2:33
The Accidental Bowel Leakage Evaluation instrument is a reliable, patient-centered measure with good validity properties. This instrument improves on currently available measures by adding patient-important domains of predictability, awareness, control, emptying, and discomfort.
Creator: Haavard D. Roervik, M.D. • André H. Campos, M.D. • Karl Styr, M.D. • Lars Ilum, M.D. • Grant K. McKinstry, M.D. • Birgitte Brandstrup, M.D., Ph.D. • Gunnar Olaison, M.D., Ph.D.
Duration: 3:34
No difference was found in symptom score 1 year postoperatively. Minimal open hemorrhoidectomy had a better effect on the hemorrhoidal prolapse and higher patient satisfaction. More patients needed treatment for recurrence after transanal hemorrhoidal dearterialization. Minimal open hemorrhoidectomy has an immediate postoperative course similar to transanal hemorrhoidal dearterialization.
Creator: Susan Galandiuk, MD
Duration: 8:50
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator: Ipek Sapci, M.D. • Emre Gorgun, M.D.
Duration: 3:54
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Rachel K. Voss, M.D., M.P.H., Jane C. Lin, M.S., Michelle T. Roper, M.D. Mohammed H. Al-Temimi, M.D., Joseph Ruan, M.D., Warren Tseng, M.D., Michael Tam, M.D., Matthew J. Sherman, M.D., Daniel D. Klaristenfeld, M.D., Marco J. Tomassi, M.D.
Duration: 2:00
In stage 2/3 rectal cancer treated with chemoradiotherapy and surgery, the addition of adjuvant chemotherapy was not associated with decreased recurrence-free survival in the entire cohort or in any subgroup, whereas tumor response to chemoradiotherapy is closely associated with disease recurrence. These findings have important consequences for treatment and surveillance decisions for patients with rectal cancer. Presurgical efforts that maximize tumor downstaging, such as total neoadjuvant therapy, may produce better oncologic outcomes than traditional adjuvant chemotherapy.
Creator: Soo Yeun Park, M.D., Jun Seok Park, M.D., Ph.D., Hye Jin Kim, M.D., In Teak Woo, M.D., In Kyu Park, M.D., Gyu-Seog Choi, M.D., Ph.D.
Duration: 2:05
Real-time indocyanine green fluorescence imaging of lymph nodes may improve the performance of more radical D3 lymph node dissection during laparoscopic right hemicolectomy for advanced right-sided colon cancer.
Creator: Traci L. Hedrick, M.D., M.S., Taryn E. Hassinger, M.D., M.S., Emma Myers, B.A., Elizabeth D. Krebs, M.D., M.Sc., David Chu, B.S., Ashley N. Charles, B.S.R.T., Sook C. Hoang, M.D., Charles M. Friel, M.D., Robert H. Thiele, M.D.
Duration: 1:56
There is significant room for improvement in baseline preoperative activity levels of patients undergoing colorectal surgery, and poor activity is associated with increased postoperative complications. These data will serve as the basis for an interventional trial investigating whether wearable devices help improve surgical outcomes through a monitored preoperative exercise program.



Creator: Yesenia Rojas-Khalil, MD
Duration: 10:03
Resumen de la edicion por Yesenia Rojas-Khalil, MD
Creator: Yesenia Rojas-Khalil, MD
Duration: 9:35
Resumen de la edicion por Yesenia Rojas-Khalil, MD
Creator: Jacopo Crippa, M.D. • Emilie Duchalais, M.D. • Nikolaos Machairas, M.D. • Amit Merchea, M.D.2 • Scott R. Kelley, M.D. • David W. Larson, M.D., M.B.A.
Duration: 1:35
The occurrence of anastomotic leak after restorative resection for rectal cancer did not impact long-term oncological outcomes in our cohort of patients.
Creator: Jung Min Kim, M.D. • Jung Won Park, M.D. • Jin Ha Lee, M.D. • Ye Hyun Park, M.D. • Soo Jung Park, M.D., Ph.D.1 • Jae Hee Cheon, M.D., Ph.D. • Won Ho Kim, M.D.,Ph.D. • Tae Il Kim, M.D., Ph.D.
Duration: 1:41
Metformin use was associated with better tumor responses and cancer-specific survival, as well as a lower risk of cancer recurrence, in patients with diabetes mellitus who had lymph node downstaging after neoadjuvant concurrent chemoradiotherapy in rectal cancer.
Creator: Jessica N. Cohan, M.D., M.A.S., Colleen Donahue, M.D., Haddon J. Pantel, M.D, Rocco Ricciardi, M.D., David A. Kleiman, M.D., M.Sc..,Thomas E. Read, M.D, Peter W. Marcello, M.D.
Duration: 2:41
An endoscopic step-up approach to colon polyps is associated with less morbidity, decreased healthcare costs, and colon preservation in 95% of patients. Additional studies are needed to evaluate long-term quality of life and polyp recurrence in this group.
Creator: Sergei Bedrikovetski, B.H.Sc.(Hons.), Nagendra N. Dudi-Venkata, M.B.B.S. GDipSurgicalEd, Hidde M. Kroon, M.D., Ph.D., James W. Moore, M.D., F.R.A.C.S., Ronald A. Hunter, M.B.B.S., F.R.A.C.S., Tarik Sammour, M.B.Ch.B., F.R.A.C.S., Ph.D.
Duration: 2:48
In this patient population, minimally invasive proctectomy demonstrated similar margin rates in comparison with open proctectomy, with a reduced length of stay but a higher overall complication rat
Creator: Sunil V. Patel, M.Sc., M.D. • Gary Ko, M.D.1 • Michael J. Raphael, M.D. • Christopher M. Booth, M.D.• Susan B. Brogly, M.Sc., Ph.D. • Maria Kalyvas, M.D. • Wenbin Li, M.Sc. • Timothy Hanna, Ph.D., M.D.
Duration: 1:59
In this large, contemporary cohort of patients with squamous cell carcinoma of the anus, the proportion of patients undergoing salvage surgery was considerably lower than previous reports. Younger age was associated with salvage surgery, and there was a suggestion of lower risk of salvage surgery with completion of chemoradiation. Patients requiring salvage surgery had poor 5-year overall survival.
Creator: Takeru Matsuda, M.D., Ph.D., Kimihiro Yamashita, M.D., Ph.D., Hiroshi Hasegawa, M.D., Ph.D., Akira Arimoto, M.D., Ph.D., Akihiro Watanabe, M.D., Masashi Yamamoto, M.D., Ph.D., Shingo Kanaji, M.D., Ph.D., Taro Oshikiri, M.D., Ph.D., Tetsu Nakamura, M.D.,
Duration: 4:56
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Susan Galandiuk, MD
Duration: 10:58
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator: Brian D. Lo, B.S. • Ira L. Leeds, M.D., M.B.A., Sc.M. • Margaret H. Sundel, M.D. Susan Gearhart, M.D. • Gabriela Nisly, B.S. • Bashar Safar, M.B.B.S.Chady Atallah, M.D. • Sandy H. Fang, M.D.
Duration: 2:22
Although minimally invasive surgical approaches have decreased postoperative complications, this effect may be reversed in frail patients. These findings challenge the belief that robotic surgery provides a favorable alternative to open surgery in frail patients.
Creator: Alice M. Couwenberg, M.D. • Martijn P.W. Intven, M.D., Ph.D. • Madelijn Leoniek Gregorowitsch, M.D. • Cees Haaring, B.Sc • Wilhelmina van Grevenstein, M.D., Ph.D. • Helena MariekeVerkooijen, M.D., Ph.D.
Duration: 3:40
Patient-reported work ability deteriorates during rectal cancer treatment. Within 24 months after diagnosis, work ability returns to pretreatment level but remains lower than that of the general population.
Creator: Yuksel Altinel, M.D. • Paul M. Cavallaro, M.D. • Rocco Ricciardi, M.D., M.P.H. • Marc S. Rubin, M.D. • Ronald Bleday, M.D. • Fraz Ahmed, M.D., M.P.H • .Liliana Bordeianou, M.D., M.P.H.
Duration: 2:31
Patients undergoing elective surgery for complex diverticulitis did not have more episodes.Instead, complex diverticulitis may be a reflection of a complicated patient, suggesting that complicated patients should have a different algorithm of care at the time of their initial presentation with diverticulitis to prevent the development of complex disease.
Creator: Britt J.P. Hupkens, M.D. • Stéphanie O. Breukink, M.D., Ph.D. • Jan H.M.B. Stoot, M.D., Ph.D. • Renee E Toebes, B.Sc.• Marit E. van der Sande, M.D. • Jarno Melenhorst, M.D., Ph.D. • Geerard L. Beets, M.D., Ph.D. • Carmen D. Dirksen, M.Sc., Ph.D
Duration: 3:24
Overall survival was good in both subgroups and comparable to literature. The mean costs per patient differ between the watch-and-wait subgroup (€6713) and the total mesorectal excision subgroup (€17,108). No comparison between the groups could be made. Based on the results of this study, the current strategy, where patients with a clinical complete response are treated in a watch-and-wait policy, and patients with an incomplete response are treated with total mesorectal excision, is likely to be (cost)saving.
Creator: Rebecca G. Rogers, M.D. • Vivian W. Sung, M.D. • Emily S. Lukacz, M.D. • Pamela Fairchild, M.D. • Lily A. Arya, M.D. • Matthew D. Barber, M.D., M.H.S. • D. Markland, M.D. • Nazema Y. Siddiqui, M.D. • Carla M. Bann, Ph.D. on behalf of the National Insti
Duration: 2:33
The Accidental Bowel Leakage Evaluation instrument is a reliable, patient-centered measure with good validity properties. This instrument improves on currently available measures by adding patient-important domains of predictability, awareness, control, emptying, and discomfort.
Creator: Haavard D. Roervik, M.D. • André H. Campos, M.D. • Karl Styr, M.D. • Lars Ilum, M.D. • Grant K. McKinstry, M.D. • Birgitte Brandstrup, M.D., Ph.D. • Gunnar Olaison, M.D., Ph.D.
Duration: 3:34
No difference was found in symptom score 1 year postoperatively. Minimal open hemorrhoidectomy had a better effect on the hemorrhoidal prolapse and higher patient satisfaction. More patients needed treatment for recurrence after transanal hemorrhoidal dearterialization. Minimal open hemorrhoidectomy has an immediate postoperative course similar to transanal hemorrhoidal dearterialization.
Creator: Susan Galandiuk, MD
Duration: 8:50
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator: Ipek Sapci, M.D. • Emre Gorgun, M.D.
Duration: 3:54
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Rachel K. Voss, M.D., M.P.H., Jane C. Lin, M.S., Michelle T. Roper, M.D. Mohammed H. Al-Temimi, M.D., Joseph Ruan, M.D., Warren Tseng, M.D., Michael Tam, M.D., Matthew J. Sherman, M.D., Daniel D. Klaristenfeld, M.D., Marco J. Tomassi, M.D.
Duration: 2:00
In stage 2/3 rectal cancer treated with chemoradiotherapy and surgery, the addition of adjuvant chemotherapy was not associated with decreased recurrence-free survival in the entire cohort or in any subgroup, whereas tumor response to chemoradiotherapy is closely associated with disease recurrence. These findings have important consequences for treatment and surveillance decisions for patients with rectal cancer. Presurgical efforts that maximize tumor downstaging, such as total neoadjuvant therapy, may produce better oncologic outcomes than traditional adjuvant chemotherapy.
Creator: Soo Yeun Park, M.D., Jun Seok Park, M.D., Ph.D., Hye Jin Kim, M.D., In Teak Woo, M.D., In Kyu Park, M.D., Gyu-Seog Choi, M.D., Ph.D.
Duration: 2:05
Real-time indocyanine green fluorescence imaging of lymph nodes may improve the performance of more radical D3 lymph node dissection during laparoscopic right hemicolectomy for advanced right-sided colon cancer.
Creator: Luigi Brusciano, M.D., Ph.D., Salvatore Tolone, M.D., Ph.D., Gianmattia Del Genio, M.D., Ph.D., Ugo Grossi, M.D., Antonio Schiattarella, M.D., Francesco Pio Piccolo, M.D., Jacopo Martellucci, M.D., Michele Schiano di Visconte, M.D., Ludovico Docimo, MD,
Duration: 3:15
Initial improvements after Gatekeeper implantation for fecal incontinence are sustained in the middle term. Accurate preoperative evaluation of coexistent clinical conditions that may negatively affect outcomes is recommended for patient selection.
Creator: Daniel L.H. Baird, M.B., Ch.B., Gianluca Pellino, M.D., Ph.D., Shahnawaz Rasheed, M.B.B.S., Ph.D., Kieran T. Power, M.Sc., Christos Kontovounisios, M.D., Ph.D., Paris P. Tekkis, M.D., Kelvin W. Ramsey, M.A., MB., B.Chir.
Duration: 2:05
The techniques appear comparable. The approaches should be considered complementary, and the choice should be individualized.
Creator: Bilgi Baca, M.D., Cigdem Benlice, M.D., Volkan Ozben, M.D., Ismail Hamzaoglu, M.D., Tayfun Karahasanoglu, M.D
Duration: 5:00
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Yesenia Rojas-Khalil, MD
Duration: 9:09
Resumen de la edicion por Yesenia Rojas-Khalil, MD
Creator: Ipek Sapci, MD; Jim Tiernan, MD, PhD, Raffi Gurunluoglu, MD; Emre Gorgun, MD
Duration: 4:45
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Zhaomin Xu, MD, MPH; Christopher T. Aquina, MD, MPH; Carla F. Justiniano, MD, MPH; Adan Z. Becerra, PhD; Francis P. Boscoe, PhD; Maria J. Schymura, PhD; Larissa K. Temple, MD, MSc; Fergal J. Fleming, MD
Duration: 2:00
The number of hospitals performing rectal cancer resections in New York State is decreasing and volume by center is increasing. There was a statistically significant difference in the mean distance traveled by patients over time. If rectal cancer resections were centralized to high-volume centers, the mean travel distance would increase by 9.5 miles. There would be a 321% increase in the number of patients having to travel 50+ miles for surgery. Any plan for centralization in New York State will require careful planning to avoid placing undue travel burden on patients.
Creator: Hamzah Abu-Sbeih, MD; Faisal S. Ali, MD; Ellie Chen, MD; Niharika Mallepally, MD; Wenyi Luo, MD; Yang Lu, MD; Wai Chin Foo, MD; Wei Qiao, PhD; Pablo C. Okhuysen, MD; Javier A. Adachi, MD; Ray Y. Hachem, MD; Mehmet Altan, MD; Robert R. Jenq, MD; Yinghong W
Duration: 3:09
The prompt diagnosis and management of neutropenic enterocolitis are critical to prevent complications. The use of granulocyte colony-stimulating factor can be beneficial to shorten the duration of neutropenia.
Creator: Mario Schootman; Donna Jeffe; Kendra Ratnapradipa; Jan Eberth; Nicholas Davidson
Duration: 3:59
Better management and prevention of anemia and sepsis among patients with diabetes mellitus may reduce their increased risk of death after colon cancer resection.
Creator: Gimon, Tamara I. M.D.1; Dykstra, Mark A. M.D., F.R.C.S.C.1; Chezar, Ksenia M.D.2; Buie, W. Donald M.D., M.Sc., F.R.C.S.C.1; MacLean, Anthony M.D., F.R.C.S.C.1
Duration: 3:57
There is a high rate of incomplete reporting of core and optional elements for malignant colorectal polyp pathology reports in Alberta. Several variables used by colorectal surgeons for decision making, such as tumor budding and depth of submucosal invasion, are not considered core elements and are infrequently reported. A pathology review by a second pathologist often results in a change in risk stratification.
Creator: Al-Masrouri, Safiya M.D., M.Sc.1; Garfinkle, Richard M.D., M.Sc.1; Al-Rashid, Faisal M.D.1; Zhao, Kaiqiong Ph.D.2; Morin, Nancy M.D.1; Ghitulescu, Gabriela A. M.D.1; Vasilevsky, Carol-Ann M.D.1; Boutros, Marylise M.D.1
Duration: 3:27
The incidence of readmission for treatment failure after an episode of diverticulitis managed nonoperatively is 6.6%, and an index episode of complicated diverticulitis is the strongest risk factor for treatment failure.
Creator: Susan Galandiuk, MD
Duration: 7:44
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator:
Duration: 4:15
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Yesenia Rojas-Khalil, MD
Duration:
Resumen de la edicion por Yesenia Rojas-Khalil, MD
Creator: Grass et al.
Duration: 2:42
Colonic decompression is effective compared to standard medical therapy alone for proximal colonic dilation or symptoms associated with acute colonic pseudo-obstruction. On segmental analysis, colonic decompression does not provide any additional benefit over standard medical therapy in improving transverse or distal colonic dilation.
Creator:
Duration: 4:24
The residual disease rate in patients treated surgically was higher than previously reported (43.2%). Incidence of recurrence in patients treated conservatively was low (4.4%). Areas of improvements have been identified in adherence to endoscopic follow-up, histopathological reporting, and potential overuse of radiological surveillance.
Creator: Compliance With Preoperative Elements of the American Society of Colon and Rectal Surgeons Rectal Cancer Surgery Checklist Improves Pathologic and Postoperative Outcomes
Duration: 4:26
A reasonable consensus was reached by the Pelvic Floor Disorders Consortium on the pelvic floor symptom measurement tools and patient-reported instruments and questionnaires that should be recommended in a routine clinical setting and as a baseline measure in clinical research addressing common pelvic floor symptoms, including a long and short form. These tools can be augmented with additional quality-of-life tools and more robust measurement tools when detailed information about a condition is needed to fine-tune decision making.
Creator: Irbaz Hameed, M.D. • Piyush Aggarwal, M.D. • Martin R. Weiser, M.D.
Duration: 3:49
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Nivethan Vela, et al
Duration: 2:54
Receipt of the open or laparoscopic surgical technique was not associated with increased risk of elevated symptom burden in the early postdischarge period.
Creator: Emma Westerduin, et al
Duration: 1:55
This study suggests that transanal minimally invasive surgery is a valid alternative to conventional top-down redo pelvic surgery for persisting pelvic sepsis or chronic sinus, with more often a laparoscopic approach for the abdominal part.
Creator: Patricia Tejedor, MD; Filippos Sagias, M.D.; Geral David, M.D:; Valerio Celentano, M.D.; Jim S Khan, PHD
Duration: 5:12
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Taryn E. Hassinger, et al.
Duration: 2:57
Editor Pick 2, Video Abstract, November 2019 Issue.
CONCLUSIONS: Enhanced recovery was associated with receiving on-time adjuvant chemotherapy. As promptinitiation of adjuvant chemotherapy improves survival in colorectal cancer, future investigation of long-term oncologic outcomes is necessary to evaluate the potential impact of enhanced recovery on survival.
Creator: Marco Bertucci Zoccali, et al.
Duration: 2:31
Editor Pick 3, Video Abstract, November 2019 Issue.
CONCLUSION: In a large cohort of patients undergoing IPAA for ulcerative colitis with at least a 5-year follow-up, anti-tumor necrosis factor exposure was the only independent risk factor for the development of pouchitis. These agents may “precondition” the pouch to develop pouchitis through alterations in the microbiome and/or local host immunity of the terminal ileum.
Creator: Nuha A. Yassin, M.B.Ch.B., M.Sc., Ph.D. • Caterina Foppa, M.D. Giuseppe Clerico, M.D.• Michele Carvello, M.D. • Matteo Sacchi, M.D. Antonino Spinelli, M.D., Ph.D.
Duration: 4:10
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Songphol Malakorn et al.
Duration: 4:02
Editor Pick 1, Video Abstract, October 2019 Issue. Conclusions of the study: Post-neoadjuvant chemoradiation lateral pelvic lymph node size ≥5 mm was strongly associated with pathologic positivity. No patients with size <5 mm had pathologically positive lymph nodes. Following lateral pelvic lymph node dissection, no patients with a positive lateral pelvic lymph node developed lateral compartment recurrence. Therefore, patients who have rectal cancer with clinical evidence of lateral pelvic lymph node metastasis and post-neoadjuvant chemoradiation lateral pelvic lymph node size ≥5 mm should be considered for lateral pelvic lymph node dissection at the time of total mesorectal excision.
Creator: Mads F. Klein et al.
Duration: 2:44
Editor Pick 3, Video Abstract, October 2019 Issue. Conclusions of the study: Based on this nationwide database study, and after multivariate and propensity score-matched analyses, there was no increased risk of positive circumferential resection margin after laparoscopic vs open rectal resection
Creator: Natalie J. Del Vecchio et al.
Duration: 2:20
Editor Pick 4, Video Abstract, October 2019 Issue. Conclusions of the study: Results suggest that patients with rectal cancer are increasingly being treated in large hospitals where they receive more guideline-recommended therapy. Although this trend is promising, patients receiving care at larger, higher-volume facilities are still the minority. Initiatives increasing patient and provider awareness of benefits of specialized care, as well as increasing referrals to large centers may improve the use of recommended treatment and ultimately improve outcomes.
Creator: Jin-Tung Liang, M.D., Ph.D., and Tzu-Chun Chen, M.D.
Duration: 5:56
Video Description (Max 100 words) Indicate a description for the video (Note, this description is indexed by the journal search engine, please be as descriptive as possible)
Creator: R. Perez*1, G. Pagin São Julião1, B. Borba Vailati1, C.M. Cabrera Ordonez1, J. Azevedo1, A. Habr-Gama1, L. Fernandez2, T. Konishi3; 1Sao Paulo, Brazil, 2Lisbon, Portugal, 3Tokyo, Japan
Duration: 4:00

2019 Best Video of the ASCRS Annual Meeting

Every year the Video-Based Education Committee of the American Society of Colon and Rectal Surgeons (ASCRS) receives high-quality videos from national and international experts for consideration for presentation at the ASCRS annual meeting. Videos are evaluated through a rigorous, anonymous, and unbiased peer-review process. The best eight are selected for podium presentation at the video session. One of these eight is selected by the Awards Committee to receive THE BARTON HOEXTER, MD, BEST VIDEO AWARD. An additional 40 videos are selected for presentation in the video room during the meeting. Five of the videos selected for podium presentation are submitted to Diseases of the Colon & Rectum to provide members of the Society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Creator: G.S. Charak*1, F.F. Quezada1, J. Garcia Aguilar1; 1New York, NY
Duration: 3:56

2019 Best Video of the ASCRS Annual Meeting

Every year the Video-Based Education Committee of the American Society of Colon and Rectal Surgeons (ASCRS) receives high-quality videos from national and international experts for consideration for presentation at the ASCRS annual meeting. Videos are evaluated through a rigorous, anonymous, and unbiased peer-review process. The best eight are selected for podium presentation at the video session. One of these eight is selected by the Awards Committee to receive THE BARTON HOEXTER, MD, BEST VIDEO AWARD. An additional 40 videos are selected for presentation in the video room during the meeting. Five of the videos selected for podium presentation are submitted to Diseases of the Colon & Rectum to provide members of the Society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Creator: K. Kawada*1, M. Yoshitomi1, S. Inamoto1, Y. Itatani1, R. Mizuno1, K. Hida1, Y. Sakai1; 1Kyoto, Japan
Duration: 4:01

2019 Best Video of the ASCRS Annual Meeting

Every year the Video-Based Education Committee of the American Society of Colon and Rectal Surgeons (ASCRS) receives high-quality videos from national and international experts for consideration for presentation at the ASCRS annual meeting. Videos are evaluated through a rigorous, anonymous, and unbiased peer-review process. The best eight are selected for podium presentation at the video session. One of these eight is selected by the Awards Committee to receive THE BARTON HOEXTER, MD, BEST VIDEO AWARD. An additional 40 videos are selected for presentation in the video room during the meeting. Five of the videos selected for podium presentation are submitted to Diseases of the Colon & Rectum to provide members of the Society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Creator: G. Low*1, E. Noren1, S. Lee1; 1Los Angeles, CA
Duration: 3:48

2019 Best Videos of the ASCRS Annual Meeting

Every year the Video-Based Education Committee of the American Society of Colon and Rectal Surgeons (ASCRS) receives high-quality videos from national and international experts for consideration for presentation at the ASCRS annual meeting. Videos are evaluated through a rigorous, anonymous, and unbiased peer-review process. The best eight are selected for podium presentation at the video session. One of these eight is selected by the Awards Committee to receive THE BARTON HOEXTER, MD, BEST VIDEO AWARD. An additional 40 videos are selected for presentation in the video room during the meeting. Five of the videos selected for podium presentation are submitted to Diseases of the Colon & Rectum to provide members of the Society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Creator: C. Harnsberger*1, K. Alavi1, J. Davids1, P. Sturrock1, C. Ellis1, J. Maykel1; 1Worcester, MA
Duration: 4:00

2019 Best Videos of the ASCRS Annual Meeting

Every year the Video-Based Education Committee of the American Society of Colon and Rectal Surgeons (ASCRS) receives high-quality videos from national and international experts for consideration for presentation at the ASCRS annual meeting. Videos are evaluated through a rigorous, anonymous, and unbiased peer-review process. The best eight are selected for podium presentation at the video session. One of these eight is selected by the Awards Committee to receive THE BARTON HOEXTER, MD, BEST VIDEO AWARD. An additional 40 videos are selected for presentation in the video room during the meeting. Five of the videos selected for podium presentation are submitted to Diseases of the Colon & Rectum to provide members of the Society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Creator: Dai Uematsu, Gaku A kiyama, Takehiko Sugihara, Akiko Magishi, Kojiro Ono, Takuya Y amaguchi, Takayuki Sano
Duration: 4:59
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Gilles Manceau M.D., Ph.D.
Duration: 3:09
Elderly patients have high morbidity with lower survival in the highest age ranges of elderly subgroups. These data should be considered when deciding on an operative approach.
Creator: Sameh Emile, M.D.
Duration: 2:37
Patients treated with external anal sphincter–sparing seton after rerouting of the fistula tract achieved quicker healing and less postoperative pain than those with conventional drainage seton. Postoperative complication and recurrence rates were comparable in both groups.
Creator: Sebastiano Biondo, M.D., Ph.D.
Duration: 3:57
Transanal hemorrhoidal dearterialization with mucopexy is associated with a shorter need for postoperative analgesia compared with vessel-sealing device hemorrhoidectomy.
Creator: Ipek Sapci, Jim P Tiernan, Emre Gorgun
Duration: 3:58
Video Vignette: AUGUST 2019
Creator: Vu, Joceline Vuong-Thu, M.D.
Duration: 2:16
The majority of colorectal cancer survivors reported unmet needs years after completion of curative-intent therapy. Patients with rectal cancer were significantly more likely to have unmet needs and may benefit from additional care during survivorship. Colorectal cancer survivorship programs should incorporate psychosocial and symptomatic care in addition to cancer surveillance.
Creator: Kerollos N. Wanis
Duration: 2:02
Given currently available data and within the limitations of a model-based decision-analytic approach, the effectiveness of routine intensive surveillance for patients after treatment of colon cancer appears, on average, to be small. Compared with testing using lower cost imaging, currently recommended strategies are associated with cost-effectiveness ratios that indicate low value according to well-accepted willingness-to-pay thresholds in the United States.
Creator: Steven J. Skube, M.D.
Duration: 2:39
Colorectal lymphoma is rare, with variable treatment approaches. Patients with noncecal involvement and chronic immunosuppression had worse overall survival. Patients with mass lesions, particularly cecal masses, are at higher risk to require urgent intervention, and primary resection should be considered.
Creator: Perez, Rodrigo Oliva, M.D., Ph.D.
Duration: 2:57
Patients with rectal cancer with node-positive cancer at baseline who develop a complete clinical response after neoadjuvant chemoradiation are not at increased risk for local tumor regrowth or development of more advanced disease at the time of recurrence. These patients seem to be safe candidates for organ-preserving strategies after achieving complete clinical response.
Creator: Tae David Kim, Jed Calata, Jean Francois Tremblay, Brian Welch, Kunal Kochar, Slawomir Marecik, John Park
Duration: 3:00
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Gianluca Pellino
Duration: 6:59
pT4a stage is an independent risk factor for worse oncologic outcome after curative colon cancer resection compared with pT3 and pT4b stages. The current pT4a-pT4b classification should be reconsidered. Of note, even in pT4a patients, 5-year carcinomatosis rate does not exceed 6%.
Creator: Isuzu Meyer, MD
Duration: 4:16
Characteristics differ between older and younger women seeking care for fecal incontinence. The differential impact and age-related phenotypes may provide useful information for patient counseling and developing management algorithms for women with fecal incontinence.
Creator: T. Bora Cengiz, Erman Aytac, and Emre Gorgun
Duration: 4:00
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Felipe Quezada-Diaz, Rosa M. Jimenez-Rodriquez, Kelly Rawdon, Julio Garcia-Aguilar
Duration: 4:42
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Christine C. Jensen, MD, MPH
Duration: 14:29
A presentation at the June 2018 annual meeting of the ASCRS. This presentation was one of several on the critical review of scientific manuscripts. The symposium was aimed at current and potential reviewers as well as those who wanted to improve their ability to evaluate manuscripts.
Creator: June Watanabe, Atsushi Ishibe, Yusuke Suwa, Hirokazu Suwa, et al.
Duration: 4:48
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Sung Uk Bae, MD
Duration: 4:11
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Jun Watanabe, Atsushi Ishibe, Yusuke Suwa, Hirokazu Suwa, Masashi Momiyama, Mitsuyoshi Ota, Itaru Endo
Duration: 4:59
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Slawomir Marecik, Christina Warner, Jean-Sebastien Trepanier, Kunal Kochar, John Park
Duration: 4:07

2018 ASCRS Barton Hoexter, MD, Best Video Award Redo repair of a recurrent rectovaginal fistula with rectal advancement flap: three-layer closure. (Slawomir Marecik, Christina Warner, Jean-Sebastien Trepanier, Kunal Kochar, John Park).

Creator: Stephanie Talutis, Jason Hall
Duration: 3:50

This video from the 2018 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Gabriel R. Chedister, Pinckney J. Maxwell, Kevin O. Delaney, Virgilio V. George
Duration: 3:52

This video from the 2018 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Bradford Sklow, Pamela Burgess
Duration: 3:34

This video from the 2018 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Wei Wang, Wenjun Xiong, Xingquan Lu, Lijie Luo, Yansheng Zheng, Jin Wan
Duration: 6:45
This video from the 2018 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Kyle G. Cologne, Megan Linnebur, Anthony J. Senagor
Duration: 5:02
Video Vignettes are peer-reviewed monthly features in DC&R that contain a brief video as the major component.
Creator: Gustavo Rossi, Juan P. Campana, Juan Achaval Rodriguez, Ricardo Mentz, Rodrigo Oliva Perez
Duration: 3:59

This video from the 2017 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Jan P. Kaminski, Phillip Fleshner, Karen Zaghiyan
Duration: 3:59

This video from the 2017 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Jean-Francois Tremblay, Slawomir Marecik, Loren Schechter, Taha Sheikh, Kunal Kochar, John Park
Duration: 3:43

This video from the 2017 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Paul Olson T, Steinhagen E, Umanskiy K, Cannon LM
Duration: 4:06

This video from the 2017 American Society of Colon and Rectal Surgeons Annual Meeting was among the five selected for podium presentation and was submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator: Dai Uematsu, Gaku Akiyama, Takehiko Sugihara, Akiko Magishi, Takuya Yamaguchi, Takayuki Sano
Duration: 4:00

Every year the Video-Based Education Committee of the American Society of Colon and Rectal Surgeons (ASCRS) receives approximately 70-80 high quality videos from national and international experts for consideration for presentation at the ASCRS annual meeting. Our committee is composed of a well-balanced group of experts in different aspects of colorectal surgery.

Videos are evaluated through a rigorous, anonymous and unbiased peer review process. The best eight are selected for podium presentation at the video session. One of these eight is selected by the Awards Committee to receive the Barton Hoexter, MD, Best Video Award. An additional 40 videos are selected for presentation in the video room during the meeting.

Five of the videos selected for podium presentation are submitted to Diseases of the Colon & Rectum to provide members of the society, trainees, and journal subscribers access to the “best of the best” of the annual meeting video session.

Alessandro Fichera and Ali Mahmood

Creator:
Duration: 5:01
Are you interested in becoming a reviewer for Diseases of the Colon & Rectum? If so, this video will help answer some of your questions. Please watch the video as the Editor-in-Chief highlights the process of becoming a reviewer for DC&R.
Creator:
Duration: 4:01
This video from the Editor-in-Chief highlights 3 fatal flaws that authors commonly make when submitting content: self-plagiarism (duplication), not adding new knowledge to the literature, and salami-slicing. Authors are highly encouraged to remember these 3 points before submitting work.
Creator:
Duration: 4:53
This video from the Editor-in-Chief discusses 10 errors that are commonly made in manuscripts submitted to DCR.
Creator:
Duration: 4:03
This video from the Editor-in-Chief discusses how to record a video abstract using your iPhone or smart phone. A few simple tips are highlighted.
Creator: Masahiro Tanaka
Duration: 3:14
Prognostic Impact of Intra-abdominal/Pelvic Inflammation Following Radical Surgery for Locally Recurrent Rectal Cancer
Creator: Inmaculada Alonso-Abreu
Duration: 4:59
Early Colonoscopy Improves the Outcome of Patients with Symptomatic Colorectal Cancer
Creator:
Duration: 4:26
This video from the Editor-in-Chief discusses the process from initial quality check, assignment to editors and reviewers, cross-checks, and copyediting.
Creator:
Duration: 6:18
This video from the Editor-in-Chief discusses 12 tips for authors whose manuscript is recommended to be revised in response to reviewer comments. Examples are provided.
Creator: Susan Galandiuk
Duration: 5:18
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator: Robert D. Madoff, MD, Editor in Chief Emeritus, Diseases of the Colon and Rectum
Duration: 11:29
Creator: Susan Galandiuk
Duration: 2:58
Summary of the issue from Editor-in-Chief Susan Galandiuk, MD
Creator:
Duration: 6:24
This video from the Editor-in-Chief discusses a newly created checklist that is designed for authors to streamline and simplify the manuscript submission process. This checklist is located in the Written Tips section as well as in the guidelines for authors.
Creator:
Duration: 4:27
The Process of Submitting a Video Abstract
Creator: Tim Bickel
Duration: 2:12
Dr. Galandiuk highlights the current issue
Creator:
Duration: 6:19
InterStim therapy; Sacral nerve stimulation; Sacral neuromodulation; Fecal incontinence.