This study was designed to compare short-term outcomes of laparoscopic vs.
open total abdominal colectomy and end ileostomy for severe ulcerative colitis
and to evaluate the impact of the initial surgical approach on subsequent operations for three-stage restorative proctocolectomy.
Perioperative demographic and outcome data for patients with severe ulcerative colitis
who underwent laparoscopic (n = 37) or open (n = 41) total abdominal colectomy at the initial stage of a three-stage restorative proctocolectomy were compared. Each stage was analyzed independently by using two-tailed t
-tests and analysis of covariance.
Patients who underwent laparoscopic total abdominal colectomy had higher serum albumin (P
= 0.0003), less inpatient narcotic usage (P
= 0.0143), faster return of bowel function (P
= 0.0001), and shorter length of stay (P
= 0.039). There were no differences in perioperative parameters for the restorative proctectomy and ileostomy closure. The laparoscopic total abdominal colectomy patients underwent subsequent restorative proctectomy 49 days sooner (P
= 0.0044) and ileostomy closure 17 days sooner (P
= 0.00003) than the open total abdominal colectomy patients.
Laparoscopic abdominal colectomy for severe ulcerative colitis
in selected patients is safe and is associated with short-term benefits that may lead to faster recovery and progression to completion of restorative proctocolectomy.