PURPOSE:: PURPOSE::Several articles have reported regression of rectal lymphoma of mucosa-associated lymphoid tissue after anti-Helicobacter pyloritherapy. It remains unclear, however, whether lymphoma of rectal mucosa-associated lymphoid tissue is related toHelicobacter pyloriinfection.
METHODS:: METHODS::A 60-year-old woman visited our hospital with a complaint of hematochezia. On colonoscopy a pale, ulcerated protrusion approximately 3.5 cm in diameter was found in the rectum. Pathologic diagnosis of a biopsy specimen was low-grade mucosa-associated lymphoid tissue lymphoma. The patient received a ten-day course of levofloxacin, and the cycle was repeated three times over seven months.
RESULTS:: RESULTS::Although persistence ofHelicobacter pyloriinfection was confirmed, the tumor regressed completely.
CONCLUSION:: CONCLUSION::Our findings in this case suggest that rectal lymphoma of mucosa-associated lymphoid tissue may be related to unknown microorganisms other thanHelicobacter pylori. Levofloxacin may be effective for treatment of rectal lymphoma of mucosa-associated lymphoid tissue regardless ofHelicobacter pyloriinfection.
aDepartment of Surgery, Fukui Prefectural Hospital, 2-8-1 Yotsui, 910-8526, Fukui-shi, Japan, e-mail: firstname.lastname@example.org
© The ASCRS 2004