Original Contributions: PDF OnlyBile composition after total proctocolectomy with interposed jejunal segment as neorectumItoh, Hideaki M.D.1; Nakahara, Shosaku M.D.2; Nakamura, Kazuhiko M.D.2; Ikeda, Shinichi M.D.2; Mibu, Ryuichi M.D.2; Ohsato, Keiichi M.D.1; Nakayama, Fumio M.D.2 Author Information 1Department of Surgery I University of Occupational and Environmental Health Yahatanishiku 807 Kitakyushu Japan 2Department of Surgery I Kyushu University Faculty of Medicine Fukuoka Japan Diseases of the Colon & Rectum: August 1989 - Volume 32 - Issue 8 - p 711-714 doi: 10.1007/BF02555779 Buy Metrics Abstract Changes of bile composition in gallbladder bile and serum chemistries were investigated in nine dogs after proctocolectomy and ileoanal anastomosis, using an interposed jejunal segment as a neorectum. A significant decrease in cholic acid and an increase in deoxycholic acid were observed 24 weeks after the operation, although there was no significant change of total bile acid and phospholipids in the bile. Concentration of cholesterol and cholesterol saturation index in bile increased after total proctocolectomy. Although serum triglyceride levels became lower compared with the nontreated control group, concentrations of total protein, serum cholesterol, total lipids, blood sugar, and electrolytes showed no significant difference. This operative procedure apparently did not impair intestinal absorption of bile acid, but did increase the biliary cholesterol saturation index. © The ASCRS 1989
