Educational DIMENSIONA Patient With Tricyclic Antidepressant Overdose With Catecholamine-Resistant Hypotension Rescued With Angiotensin II A Case ReportFerdowsali, Jacqueline DNP, MSN, BSN, ACNPC-AG; Ferdowsali, Kameron MDAuthor Information Jacqueline Ferdowsali, DNP, MSN, BSN, ACNPC-AG, is an assistant professor at the University of Nevada Reno. She is the track coordinator for the adult gerontology acute care nurse practitioner program. Her clinical practice is as an adult gerontology acute care nurse practitioner with a pulmonary and tele-medicine service. Kameron Ferdowsali, MD, is an intensivist at Peace Health Medical Center. He also manages a tele-medicine critical care service. He has vast experience treating individuals with shock states. K.F. reports receiving honoraria from La Jolla Pharmaceutical Company. K.F. is part of the speaking bureau for La Jolla Pharmaceuticals. He provides US Food and Drug Administration–approved education about angiotensin II. The honoraria include payments for travel expenses and time spent at speaking engagements. K.F. reports no other financial interests or involvement in work in the company. The authors have disclosed that they have no significant relationship with, or financial interest in, any commercial companies pertaining to this article. Address correspondence and reprint requests to: Jacqueline Ferdowsali, DNP, MSN, BSN, ACNPC-AG, Orvis School of Nursing, University of Nevada Reno, 1664 N. Virginia St., Reno, NV, 89557 (firstname.lastname@example.org). Dimensions of Critical Care Nursing: May/June 2020 - Volume 39 - Issue 3 - p 140-144 doi: 10.1097/DCC.0000000000000414 Buy Metrics Abstract This case report explores the novel use of angiotensin II (Giapreza) for the treatment of vasodilation in the setting of a tricyclic overdose. The purpose of this case is to describe how the use of angiotensin II can improve hemodynamic parameters and result in a dose reduction of other catecholamine vasopressors in vasodilatory shock. The use of angiotensin II is new to clinical practice and has the potential to change outcomes for patients. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.