Research DIMENSIONEvaluation of an Evidence-Based Practice Implementation Prophylactic Amiodarone Following Coronary Artery RevascularizationHoffmann, Mary C. MSN, RN, CCRN-CSC, ACNP-BC Author Information Mary C. Hoffmann, MSN, RN, CCRN-CSC, ACNP-BC, is an acute care nurse practitioner at The Christ Hospital, Cincinnati, Ohio. No funding was received for this study. The author has disclosed that she has no significant relationships with, or financial interest in any commercial companies pertaining to this article. Address correspondence and reprint requests to: Mary C. Hoffmann, MSN, RN, CCRN-CSC, ACNP-BC, 5226 Willowood Ave, Cincinnati, OH 45238 ([email protected]). Dimensions of Critical Care Nursing: May/June 2012 - Volume 31 - Issue 3 - p 193-201 doi: 10.1097/DCC.0b013e31824e0150 Buy Metrics AbstractIn Brief Postoperative atrial fibrillation is the most frequent dysrhythmia following coronary artery bypass grafting and is associated with complications, additional therapy, and longer hospital stays. Prophylactic amiodarone protocols have been validated as safe and beneficial in the prevention of atrial fibrillation following cardiac surgery. This study evaluates the use of our current treatment protocol, given prophylactically, as feasible and effective in producing similar outcomes in postoperative atrial fibrillation reduction as well as identifies any perioperative risk factors associated with this arrhythmia. This article presents the results of a study conducted to evaluate the safety and effectiveness of a more practical use of a new perioperative amiodarone protocol. In addition, postoperative atrial fibrillation is discussed—incidence, pathogenesis, complications, and management. © 2012 Lippincott Williams & Wilkins, Inc.