Subglottic Secretion Aspiration in the Prevention of Ventilator-Associated Pneumonia: A Review of the LiteratureScherzer, Rachel MSN, RNDimensions of Critical Care Nursing: November-December 2010 - Volume 29 - Issue 6 - p 276-280 doi: 10.1097/DCC.0b013e3181f0bfd1 Clinical DIMENSION Abstract In Brief Author Information Ventilator-associated pneumonia is a common nosocomial infection that results in both negative patient outcomes and increased health care costs. Recently, many efforts have been targeted at ventilator-associated pneumonia prevention, including the practice of subglottic secretion aspiration. Six randomized control studies examining the effectiveness of subglottic secretion aspiration in the prevention of ventilator-associated pneumonia were reviewed for this article. Results consistently show that subglottic secretion aspiration significantly reduces the incidence of ventilator-associated pneumonia in a variety of patient populations. Despite these findings, this practice is limited in clinical settings. This clinical practice should be implemented in individuals requiring mechanical ventilation to reduce the incidence of ventilator-associated pneumonia. Ventilator-associated pneumonia is a common nosocomial infection that results in negative patient outcomes and increased costs. Six randomized control studies examining the effectiveness of subglottic secretion aspiration are reviewed in this article. Rachel Scherzer, MSN, RN, is nursing instructor at Thomas Jefferson University. She also works as a stafff nurse at Thomas Jefferson University Hospital in a Medical Respiratory Intensive Care Unit. Address correspondence and reprint requests to: Rachel Scherzer, MSN, RN, Jefferson School of Nursing, Suite 1123-Edison Building, 130 South 9th Street Philadelphia, PA 19107 (Rachel.Scherzer@jefferson.edu). © 2010 Lippincott Williams & Wilkins, Inc.