Clinical DIMENSION: Platelets in Critical IllnessPivotal Role of Platelets in Critical Illness Evidence Behind Clinical InterventionsCollins, Angela S. DSN, RN, CCNS, APRNBC Author Information ABOUT THE AUTHOR Angela S. Collins, DSN, RN, CCNS, APRNBC, is a Clinical Associate Professor of Nursing with a clinical focus in critical care, pharmacology, and adult health. After receiving an AS and BSN from Samford University in 1976 and 1977, she obtained an MSN from Medical College of Georgia in 1978, and completed a DSN from the University of Alabama in Birmingham in 1991. Dr. Collins has a 27-year history of clinical nursing experience. Areas of publication and presentation include cardiovascular pharmacology, pathophysiology, postanesthesia care, and numerous surgical topics. Dr. Collins holds certifications as a Clinical Nurse Specialist in Critical Care and Medical Surgical Nursing. She is active in the American Association of Critical Care Nursing and was the recipient of the Baptist Health System of Alabama Mission Awards of Excellence and Resourcefulness in both 1998 and 2000. Dr. Collins serves the college by teaching and providing advanced practice nursing resources throughout Alabama. Address correspondence and reprint requests to Angela S. Collins, DSN, RN, CCNS, APRNBC, University of Alabama Hospital, Box 870358, Tuscaloosa, AL 35487 ([email protected]). Dimensions of Critical Care Nursing: September 2004 - Volume 23 - Issue 5 - p 217-221 Buy AbstractIn Brief Arteriosclerosis, chronic renal failure, and diabetes are all diseases in which the platelet cycle plays an important role. Effective interventions for these diseases are emerging from vascular biology in general and from the study of platelets in particular. Platelet cell processes are powerful modulators of immunology, thrombosis, fibrinolysis, and angiogenic responses. Platelet active drugs intervene in platelet activation, adhesion, aggregation, and secretion. The purpose of this article is to link the unfolding of platelet cell processes and the impact of platelet active medication therapy to the care of critically ill patients with selected diseases. This article presents the importance of platelets and the impact of medication therapy in critcally ill patients. © 2004 Lippincott Williams & Wilkins, Inc.