Original ArticlesThe Association Between Modified Intracoronary Thrombus Grade and Cardiovascular Risk Factors and Initial Laboratory Findings in Patients Undergoing Primary Percutaneous Coronary InterventionNozari, Younes MD; Geraiely, Babak MD; Kassaian, Seyed Ebrahim MD; Saroukhani, Sepideh MD; Mortazavi, Seyedeh Hamideh MD Author Information From the Department of Interventional Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Received for publication December 20, 2018; accepted March 25, 2019. Reprints: Babak Geraiely, MD, Tehran Heart Center, Tehran University of Medical Sciences, North Kargar Street, PO Box: 1411713138, Tehran, Iran. E-mail: [email protected]. Critical Pathways in Cardiology: September 2019 - Volume 18 - Issue 3 - p 135-138 doi: 10.1097/HPC.0000000000000185 Buy Metrics Abstract The thrombus burden has been shown to affect the immediate results of primary coronary intervention and the outcome of the patients. The aim of the present study was to determine the cardiovascular risk factors and initial laboratory findings associated with angiographic thrombotic grade based on the new reclassified grading method. A total of 394 consecutive patients presenting with a first ST-elevation myocardial infarction treated by primary coronary intervention were retrospectively evaluated between March 2014 and March 2017. Patients were divided into 2 groups of low thrombus grade (grades 1–3) and high thrombus grade (grade 4). The results showed that the patients with high thrombus grade had markedly higher white blood cell (WBC) counts, platelet counts, and initial troponin levels (P values were <0.001, 0.004, and <0.001, respectively). After logistic regression analysis, high WBC count had the strongest association with high thrombus grade [odds ratio: 3.185, 95% confidence interval: 1.349–7.520; P = 0.008]. The initial troponin level also had significant association with high thrombus grade, whereas high platelet count had a borderline statistical significance (odds ratio: 2.250, 95% confidence interval: 0.928–5.459; P = 0.073). In conclusion, the present study demonstrated that high WBC and higher levels of baseline troponin were associated with high angiographic thrombus grade in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.