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Long-term multimodality imaging follow-up of ST-segment elevation myocardial infarction patients treated with bioresorbable vascular scaffold: advantages and challenges

Eriksen, Erlend^a,b; Neghabat, Omeed^c,d; Larsen, Terje H.^a,e; Saeed, Sahrai^a; Bleie, Øyvind^a

Author Information

^aDepartment of Heart Disease, Haukeland University Hospital

^bDepartment of Clinical Science, University of Bergen, Bergen, Norway

^cDepartment of Cardiology, Aarhus University Hospital

^dDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark

^eDepartment of Biomedicine, University of Bergen, Bergen, Norway

Received 4 February 2023 Accepted 21 April 2023.

Correspondence to Dr Erlend Eriksen, MD, Department of Heart Disease, Haukeland University Hospital, Jonas Lies Vei 65, Bergen 5021, Norway, Tel: +47 55972220; e-mail: [email protected]

Coronary Artery Disease 34(6):p 415-424, September 2023. | DOI: 10.1097/MCA.0000000000001249

Abstract

Background:

Multislice computed tomography (MSCT) offers a non-invasive method of imaging bioresorbable scaffolds (BRS).

Objectives:

To investigate the advantages and challenges using MSCT in the follow-up after BRS implantation.

Method:

The BRS cohort consisting of 31 patients in the ‘BRS in STEMI’ trial was examined by multimodality imaging and followed long-term. Minimum lumen area (MLA) and average lumen area (ALA) were examined 12 and 36 months after BRS implantation with MSCT. Optical coherence tomography (OCT) at 12 months was used as a reference.

Results:

Measured by MSCT, the mean MLA was 0.05 ± 1.32 mm² (P = 0.85), but ALA was 1.32 (±2.59 mm², P = 0.015) greater than by OCT. ALA and MLA did not change significantly from 12 to 36 months. MSCT identified all cases of restenosis but missed one patient with massive malapposition.

Conclusion:

Our data support using MSCT in the follow-up after BRS implantation. Invasive investigation should still be considered for patients with unexplained symptoms.

Article Keywords

Keywords
bioresorbable vascular scaffold, multimodality imaging follow, optical coherence tomography, ST-segment elevation myocardial infarction

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Long-term multimodality imaging follow-up of ST-segment elevation myocardial infarction patients treated with bioresorbable vascular scaffold: advantages and challenges