Review articleRecurrent spontaneous coronary artery dissectionXu, Minmina; Wang, Jianb; Yuan, Kangzhengc; Luo, Xiaoyana; Liu, Fangmeic; Deng, Minc; Wang, Daxind Author Information aDepartment of Cardiology, Clinical Medical College, Dalian Medical University, Dalian, Liaoning bDepartment of Cardiology, Taizhou People’s Hospital, Taizhou cDepartment of Cardiology, Northern Jiangsu People’s Hospital dDepartment of Cardiology, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China Received 8 February 2022 Accepted 24 September 2022. Corresponding to Daxin Wang, MD, Clinical Medical College, Yangzhou University, 88#, South University Ave, Yangzhou 225009, Jiangsu, China, Tel/fax: +86 0514 8737 3039; e-mail: [email protected], [email protected] Coronary Artery Disease: November 23, 2022 - Volume - Issue - 10.1097/MCA.0000000000001199 doi: 10.1097/MCA.0000000000001199 Buy PAP Metrics Abstract Spontaneous coronary artery dissection (SCAD) is a significant cause of myocardial infarction (MI) and is more prevalent in pregnancy. The disease is being increasingly appreciated and diagnosed with the development and application of coronary angiography and intravascular imaging. Recurrent spontaneous coronary artery dissection (R-SCAD) is relatively common, with recurrence rates ranging from 8 to 27%. R-SCAD usually involves anatomical sites different from the original SCAD lesion and can cause MI, ventricular arrhythmias, and cardiogenic shock. This study aims to conduct a comprehensive review of R-SCAD to identify early risk factors and guide prevention policies and interventions. In addition, the risk of R-SCAD in subsequent pregnancies in women with a history of SCAD is discussed. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.