Reviews in DepthThe right ventricle in pulmonary hypertensionChin, Kelly M.; Kim, Nick H.S.; Rubin, Lewis J.Editor(s): Goldstein, James Author Information Division of Pulmonary and Critical Care Medicine, University of California, San Diego School of Medicine, La Jolla, California, USA Correspondence and requests for reprints to Lewis J. Rubin, 9300 Campus Point Drive M/C 7381, La Jolla, CA 92037-1300, USA E-mail: [email protected] Coronary Artery Disease: February 2005 - Volume 16 - Issue 1 - p 13-18 Buy Abstract Pulmonary arterial hypertension (PAH) is a term used to classify a variety of conditions that share in common an injury to the pulmonary vasculature that produces elevations in pulmonary arterial pressure. However, it is the integrity of right ventricular function, rather than the degree of vascular injury, that is the major determinant of symptoms and survival in PAH. The article will review the normal structure and function of the right ventricle and summarize the impact of PAH and its treatments on right ventricular function. © 2005 Lippincott Williams & Wilkins, Inc.