Reviews in DepthClinical contribution of the collateral circulation to myocardial protectionSmith, Robert D.; Ilsley, Charles D.J.Section Editor(s): Mason, Mark J. Author Information Department of Cardiology, Harefield Hospital, Royal Brompton and Harefield NHS Trust, Harefield, Middlesex, UK Correspondence and requests for reprints to Department of Cardiology, Harefield Hospital, Royal Brompton and Harefield NHS Trust, Harefield, Middlesex, UK Tel: +44 19895 823737; fax: +44 1895 828962; e-mail: [email protected] Coronary Artery Disease: November 2004 - Volume 15 - Issue 7 - p 393-398 Buy Abstract This section describes the clinical evidence for benefit from coronary collateral channels. There is data to suggest the presence of a protective effect in patients sustaining myocardial infarction regardless of whether they receive reperfusion therapy, and whether the collaterals were preformed. The role of pre-infarction angina in stimulating collateral development remains a contentious issue. © 2004 Lippincott Williams & Wilkins, Inc.