Basic InvestigationsThe Use of the Fugo Blade in Corneal Surgery: A Preliminary Animal StudyPeponis, Vasileios MD; Rosenberg, Pinchas MD; Reddy, Satya V MD; Herz, Joshua B MD; Kaufman, Herbert E MDAuthor Information From the LSU Eye Center, Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana. Received for publication Aug 11, 2004; revision received Mar 9, 2005; accepted Mar 19, 2005. This work was supported by USPHS grant P30 EY002377 (departmental core grant) from the National Eye Institute and an unrestricted grant from Research to Prevent Blindness, Inc, New York, NY. The authors have no financial interest in any of the products described herein. Reprints: Herbert E. Kaufman, MD, LSU Eye Center, 2020 Gravier Street, Suite B, New Orleans, LA 70112 (e-mail: firstname.lastname@example.org). Cornea: February 2006 - Volume 25 - Issue 2 - p 206-208 doi: 10.1097/01.ico.0000179927.12899.bb Buy Metrics Abstract Purpose: To evaluate the performance of the Fugo Blade in cutting corneal tissue in animals, both in vitro and in vivo. Methods: Corneal incisions were made on pig eyes using the Fugo Blade. The histologic characteristics of these cuts were then evaluated. Similar cuts were also performed in rabbit corneas in vivo and compared with cuts performed with mechanical blades. The rabbits were euthanized, and the corneas were obtained for histopathologic examination 14 days after surgery. Results: Slit-lamp examinations and histologic findings showed that the Fugo Blade can produce sharp cuts in the cornea with minimal tissue damage beyond the edges of the incisions. It cuts without resistance and permits normal wound healing. Conclusions: Although the Fugo Blade is currently approved by the Food and Drug Administration for anterior capsulotomy, our study demonstrates that the Fugo Blade can safely and quickly produce resistance-free cuts in corneal tissue in animals, opening additional avenues for use of this device in corneal surgery. Copyright © 2006 Wolters Kluwer Health, Inc. All rights reserved.