Clinical ScienceAn Unexpected Incidence of Ocular Surface Neoplasia on Pterygium Surgery. A Retrospective Clinical and Histopathological ReportMejía, Luis F. MD; Zapata, Melissa MD; Gil, Juan C. MD Author Information Department of Ophthalmology, CES University, Medellín, Colombia. Correspondence: Luis F. Mejía, MD, Department of Ophthalmology, CES University, Cra 25A #1-31, Ofic 914, Medellín 050021, Colombia (e-mail: [email protected]). The authors have no funding or conflicts of interest to disclose. Cornea: August 2021 - Volume 40 - Issue 8 - p 1002-1006 doi: 10.1097/ICO.0000000000002586 Buy Metrics Abstract Purpose: To report the unexpected finding of ocular surface neoplasia (OSSN) on conjunctival tissue removed during pterygium surgery and subjected to histopathology analysis. Methods: This is an observational, descriptive retrospective study in which all the samples removed during surgery between 1997 and 2020 with a clinical diagnosis of pterygium were sent for histopathology analysis in which an unexpected OSSN was found. Results: There were 461 cases with a preoperative diagnosis of pterygium, with a mean age of 30.14 ± 10.6 years. In this group, there was an unexpected finding of OSSN in 69 cases (14.96%) of the surgical samples, with a mean age of 46 ± 8.2 years (31.86 ± 12.13). Conclusions: The unexpected coincidence of pterygium and OSSN is frequent, although varies depending on the geographical location. We recommend performing a histopathology analysis on every pterygium removed. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.