Case ReportYAG Laser Treatment for Epithelial Ingrowth in Descemet Membrane Endothelial Keratoplasty InterfaceJenkins, Sabrina G. BS; Jun, Albert S. MD, PhD; Woreta, Fasika A. MD, MPH; Srikumaran, Divya MDAuthor Information Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD. Correspondence: Divya Srikumaran, MD, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 600 North Wolfe St, Wilmer B-31, Baltimore, MD 21287 (e-mail: [email protected]). The authors have no funding or conflicts of interest to disclose. Cornea: November 2020 - Volume 39 - Issue 11 - p 1439-1441 doi: 10.1097/ICO.0000000000002367 Buy Metrics Abstract Purpose: To present a case of epithelial ingrowth in the graft-host interface after Descemet membrane endothelial keratoplasty (DMEK) surgery that was successfully treated with a yttrium aluminum garnet (YAG) laser. Methods: A 53-year-old white woman underwent uncomplicated combined cataract and DMEK surgery in her right eye. At her regularly scheduled 6-month follow-up visit, an asymptomatic dense white interface opacity was observed. Confocal imaging confirmed the presence of epithelial cells. After initial close observation, the opacity was noted to be slowly growing and the patient underwent YAG laser treatment for the opacity. Results: The patient remained stable 4 months postlaser treatment with no recurrence of epithelial ingrowth. Conclusions: YAG laser treatment may be a safe and effective way to treat early-stage epithelial ingrowth in the interface after DMEK surgery. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.