Techniques“Double-Bubble” Descemet Membrane Endothelial Keratoplasty Unfolding in Eyes With Deep Anterior Chambers and Anterior Chamber Intraocular LensesParker, Jack S. MD, PhD*,†; Parker, John S. MD*; Melles, Gerrit R.J. MD, PhD†,‡,§Author Information *Parker Cornea, Birmingham, AL; †NIIOS-USA, San Diego; ‡Netherlands Institute for Innovative Ocular Surgery (NIIOS), Rotterdam, The Netherlands; and §Melles Cornea Clinic Rotterdam, The Netherlands. Correspondence: Jack S. Parker, MD, PhD, Callahan Eye Hospital, 701 University Blvd, Birmingham, AL 35222. (e-mail: firstname.lastname@example.org). The authors have no funding or conflicts of interest to disclose. Cornea: July 2020 - Volume 39 - Issue 7 - p 919-923 doi: 10.1097/ICO.0000000000002250 Buy Metrics Abstract Purpose: To describe a standardized technique for Descemet membrane endothelial keratoplasty unfolding in eyes with deep anterior chambers and anterior chamber intraocular lenses (ACIOLs). Methods: Two air bubbles are used simultaneously: the first placed on top of the graft and the second one underneath. Results: The 2 bubbles work in concert—the bubble on top props the tissue partially open, while the bubble underneath levitates the graft away from the ACIOL and provides support for subsequent unfolding maneuvers. Conclusions: By sandwiching the graft between 2 bubbles, unfolding may proceed away from physical contact with the ACIOL, even in eyes with hyper-deep chambers. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.