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Seroprevalence of Anti-HIV-1, Anti-HIV-2, Hepatitis B Surface Antigen, and Anti-HCV in Eye Donors in a Tertiary Eye Hospital, Chennai, India, in the Past 13 years (2005–2017)

Kulandhai, Lily Therese, PhD; Bhagavathi, Hema, MSc; Krishnan, Selvi, BSc; Krishnan, Kaviyarasan, MSc; Balasubramaniyam, Mahalakshmi, PhD; Madhavan, Hajib Naraharirao, PhD

doi: 10.1097/ICO.0000000000001926
Basic Investigation
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Purpose: To understand the seroprevalence of HIV, hepatitis B surface antigen (HBsAg), and hepatitis C virus (HCV) in serum samples collected from eye donors between 2005 and 2017 at Sankara Nethralaya, Chennai, India.

Method: The reports of 7136 eye donors serologically screened for antibodies to HIV-1 and HIV-2, HBsAg, and antibodies to HCV were retrospectively analyzed.

Result: Among the 7136 serum samples screened during this study period, the serum samples of 14 donors (0.20%) were reactive to HIV-1 antibodies, 78 donors (1.09%) were positive for detection of HBsAg, and 37 donors (0.52%) were positive for HCV antibodies. Of interest, coinfections of HIV-1 and HBV, and HIV-1 and HCV were detected in 2 and 1 serum sample of the eye donors, respectively.

Conclusions: This retrospective study indicates that there is a trend of reduction in the seropositivity for HIV, HBV, and HCV among eye donors in Chennai over the last decade.

L&T Microbiology Research Centre, Vision Research Foundation, Chennai, Tamil Nadu, India.

Correspondence: Lily Therese Kulandai, PhD, Larsen & Toubro Microbiology Research Centre, Vision Research Foundation, VI Floor, Kamal Nayan Bajaj Institute for Vision and Ophthalmology Building, 41, College Rd, Chennai, Tamil Nadu 600 006, India (e-mail: drklt@snmail.org).

The authors have no funding or conflicts of interest to disclose.

Received August 24, 2018

Received in revised form January 08, 2019

Accepted February 03, 2019

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