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Intraoperative Optical Coherence Tomography to Guide Corneal Biopsy

A Case Report

Schmidt, Eleanor M., BA*; Stiefel, Hillary C., MD; Houghton, Donald C., MD; Chamberlain, Winston D., MD, PhD

doi: 10.1097/ICO.0000000000001873
Case Report
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Purpose: To report on a new application of intraoperative optical coherence tomography (OCT) as a real-time imaging tool to help guide corneal biopsy.

Methods: Single case report. After the negative result of a corneal biopsy, we used intraoperative OCT during repeat biopsy to assist in depth and acquisition of an anterior stromal opacity suspected to be immunoglobulin deposits.

Results: The use of intraoperative OCT is a novel tool, which assisted in successful identification and conservative biopsy of corneal immunoglobulin deposits.

Conclusions: Intraoperative OCT is a novel tool that assists in the identification and location of corneal pathology for biopsy.

*Oregon Health & Science University, School of Medicine, Portland, OR;

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR; and

Department of Pathology, Oregon Health & Science University, Portland, OR.

Correspondence: Winston D. Chamberlain, MD, PhD, Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239 (e-mail: chamberw@ohsu.edu).

The authors have no funding or conflicts of interest to disclose.

Received October 25, 2018

Received in revised form December 04, 2018

Accepted December 06, 2018

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