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Management of Type 2 Bubble Formed During Big Bubble Deep Anterior Lamellar Keratoplasty

Goweida, Mohamed Bahgat FRCS(Glasg), PhD*,†,‡; Ragab, Ahmed Mahmoud FRCSEd*; Liu, Christopher FRCOphth, FRCSEd, CertLRS†,‡,§

doi: 10.1097/ICO.0000000000001815
Clinical Science
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Purpose: To review the outcome of 3 techniques for managing type 2 bubbles (between Descemet's membrane [DM] and stroma) formed during big bubble (BB) deep anterior lamellar keratoplasty (DALK) in different corneal pathologies.

Methods: This is an interventional case series study of patients with type 2 bubbles formed during BB DALK. Three techniques to complete DALK are described: the first is a DM baring technique similar to Anwar's BB technique, the second is the microbubble incision technique to preserve the pre-Descemetic support to DM, and the third is done in eyes with combined type 1 and type 2 BB (mixed bubble), where the type 1 bubble is opened and surgery is completed avoiding the type 2 bubble.

Results: Thirty-one eyes of 31 patients were included. The DM baring technique has a high rate of conversion to penetrating keratoplasty (12 of 16 eyes). In the other 2 techniques (which did not bare DM), DALK could be completed in all 15 cases with intact DM. Double anterior chamber is a relatively common complication after type 2 BB, even with an intact DM.

Conclusions: DM baring techniques should be avoided in eyes with type 2 BB. Instead, deep stromal dissection searching for an incomplete type 1 bubble or using one of the manual dissection techniques as a guide to the clear pre-Descemetic stroma is safer and more reliable.

*Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt;

Sussex Eye Hospital, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom;

Brighton and Sussex Medical School, Brighton, United Kingdom; and

§Tongdean Eye Clinic, Hove, United Kingdom.

Correspondence: Mohamed Bahgat Goweida, FRCS(Glasg), PhD, Department of Ophthalmology, Faculty of Medicine, Alexandria University, El-Khartoum Square, Azarita Medical Campus, Alexandria, Egypt (e-mail: mbahgat@yahoo.com).

The authors have no funding or conflicts of interest to disclose.

Received March 04, 2018

Accepted October 04, 2018

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