Case ReportThree Hundred Sixty-Degree Fuchs Superficial Marginal Keratitis Managed With Annular Lamellar KeratoplastyCheung, Albert Y. MD*,†; Sarnicola, Enrica MD*,‡; Kurji, Khaliq H. MD*,†; Genereux, Brad M. OD*,†; Holland, Edward J. MD*,†Author Information *Cincinnati Eye Institute, Cincinnati, OH; †Department of Ophthalmology, University of Cincinnati, Cincinnati, OH; and ‡Department of Medicine Surgery and Neuroscience, University of Siena, Siena, Italy. Reprints: Edward J. Holland, MD, 580 South Loop Rd., Suite 200 Edgewood, KY 41017 (e-mail: [email protected]). E. J. Holland has consulted for Alcon Laboratories, Allergan, Bausch & Lomb, Kala Pharmaceuticals, Mati Pharmaceuticals, Omeros, PRN, RPS, Senju Pharmaceuticals, Shire, TearLab, and TearScience. The authors have no funding or conflicts of interest to disclose. Cornea: February 2018 - Volume 37 - Issue 2 - p 260-262 doi: 10.1097/ICO.0000000000001433 Buy Metrics Abstract Purpose: To report a case of extensive Fuchs superficial marginal keratitis managed with annular lamellar keratoplasty. Methods: Interventional case report. Results: A 72-year-old man presented with 20/80 best-corrected visual acuity in his left eye and demonstrated 360-degree peripheral deep immune stromal keratitis and pseudopterygia with peripheral stromal thinning. During superficial keratectomy with amniotic membrane transplantation, the thin cornea was perforated while excising pseudopterygia in the superonasal quadrant. Surgery was aborted. Anterior segment optical coherence tomography demonstrated a severely thinned cornea (240 μm nasally, 360 μm temporally) with overlying pseudopterygia peripherally. After allowing 3 months for the cornea to heal, the decision was made to perform lamellar annular (or “donut”) keratoplasty. The patient had an unremarkable postoperative course, with 20/50 best-corrected visual acuity 10 months after keratoplasty. Conclusions: We report an extensive case of Fuchs superficial marginal keratitis treated with 360-degree annular lamellar keratoplasty. This technique provides tectonic support to decrease the likelihood of future perforation while also improving vision by modifying the ectatic cornea. Anterior segment optical coherence tomography may be a helpful tool preoperatively to avoid severely thinned areas (eg, during pseduopterygium removal) and to ensure complete removal of the ectatic cornea. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.