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Planned Descemetorhexis Without Endothelial Keratoplasty in Eyes With Fuchs Corneal Endothelial Dystrophy

Koenig, Steven B. MD

doi: 10.1097/ICO.0000000000000531
Case Report
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Purpose: The purpose of this study was to describe the results of a simple 6-mm central descemetorhexis in eyes with Fuchs corneal endothelial dystrophy.

Methods: This prospective nonrandomized IRB approved pilot study was performed on 2 patients with coexisting Fuchs dystrophy and cataract who underwent combined phacoemulsification and descemetorhexis without endothelial transplantation.

Results: In each patient, residual disciform stromal edema corresponded to the diameter of the descemetorhexis and led to an associated loss of visual acuity. Vision improved to 20/40 −1 in case 1 and to 150 −1 in case 2 during a follow-up period of 12 and 10 months, respectively. Endothelial cell repopulation of the descemetorhexis could not be confirmed because of the presence of persistent corneal edema.

Conclusions: Because of the relatively poor postoperative visual acuity and slow visual recovery, a simple descemetorhexis is not an acceptable form of therapy for eyes with Fuchs corneal endothelial dystrophy.

Department of Ophthalmology, Froedtert and the Medical College of Wisconsin, Milwaukee, WI.

Reprints: Steven B. Koenig, MD, Department of Ophthalmology, Medical College of Wisconsin, 925 N. 87th St, Milwaukee, WI 53226 (e-mail: skoenig@mcw.edu).

This research was supported by a grant from Research to Prevent Blindness and by private donation from Dr Myrna Larson and Dr Nelson A. Moffat.

The author has no conflicts of interest to disclose.

Received March 20, 2015

Received in revised form May 19, 2015

Accepted May 20, 2015

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