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Influence of Axial Length on Conjunctivochalasis

Mimura, Tatsuya MD; Yamagami, Satoru MD; Kamei, Yuko MD; Goto, Mari MD; Matsubara, Masao MD

doi: 10.1097/ICO.0b013e318292b7a2
Clinical Science

Purpose: To investigate the relation between the severity of conjunctivochalasis and the axial length (AL) of the eyeball.

Methods: A prospective nonrandomized study was performed on 165 patients aged 51 to 88 years. The age, gender, medical history, ocular history, grade and other parameters of inferior conjunctivochalasis (classified as nasal, middle, and temporal), and AL were determined in all patients. Patients were divided into a short AL group (≤22.0 mm), a medium AL group (>22.0 to ≤24.0 mm), and a long AL group (>24.0 mm).

Results: The short AL group tended to have higher grades of temporal and nasal conjunctivochalasis compared with the medium and long AL groups. Multivariate logistic regression analysis showed that the total conjunctivochalasis score (the sum of the scores for the temporal, middle, and nasal regions) was significantly associated with the age [odds ratio (OR) = 1.32, P = 0.001] and the AL (OR = 0.81, P = 0.029). In addition, the AL was independently associated with the grade of conjunctivochalasis after adjustment for age (OR = 0.80, P = 0.020).

Conclusions: This was the first assessment of the relationship between the AL and the grade of conjunctivochalasis. Our findings suggest that the severity of conjunctivochalasis is dependent on the AL, with a short AL contributing to the pathogenesis of conjunctivochalasis.

*Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan; and

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Reprints: Tatsuya Mimura, Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, 2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan (e-mail:

Supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan and by a Health Labour Sciences Research Grant from the Ministry of Health Labour and Welfare of Japan.

The authors have no conflicts of interest to disclose.

Received February 22, 2013

Accepted March 18, 2013

Copyright © 2013 Wolters Kluwer Health, Inc. All rights reserved.