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Corneal Autograft and Allograft in a 10-Month-Old Premature Boy With Acquired Bilateral Corneal Opacities

Tannen, Bradford MD; Zarbin, Marco A MD, PhD; Bhagat, Neelakshi MD; Wagner, Rudolph MD; Chu, David S MD

doi: 10.1097/ICO.0b013e3182031a72
Case Report

Purpose: To report a case in which corneal autograft and allograft were performed in a 10.5-month-old, ex 24-week, premature boy with bilateral corneal opacities from infectious keratitis.

Methods: Case report based upon chart review.

Results: At 3 years, the corneal autograft is clear without vascular ingrowth. After transplantation, the clarity of the autograft improved markedly and unexpectedly from its pretransplantation appearance. The child fixes and follows and has central steady maintained fixation at near with a spectacle correction of +11.00 diopters. The allografted cornea is opaque with 360 degrees of vascular ingrowth. This eye is phthisical with no response to light.

Conclusions: In circumstances in which a viable cornea is available from the patient's worse prognosis eye, a corneal autograft is a potential treatment option.

From the *Mount Sinai School of Medicine, Department of Ophthalmology, New York NY; and †University of Medicine and Dentistry New Jersey, Institute of Ophthalmology and Visual Science, Newark, NJ.

Received for publication September 17, 2009; revision received September 19, 2010; accepted October 5, 2010.

Reprints: Bradford Tannen, MD, Assistant Professor of Ophthalmology, Mount Sinai School of Medicine, Department of Ophthalmology, One Gustave L. Levy Place, Box 1183, New York, NY 10029 (email:

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