Clinical SciencePost–Laser Assisted In Situ Keratomileusis Epithelial Ingrowth and Its Relation to Pretreatment Refractive ErrorMohamed, Tarek A MD; Hoffman, Richard S MD; Fine, I Howard MD; Packer, Mark MDAuthor Information From the *Ophthalmology Department, Assiut University Hospitals, Assiut, Egypt; and †Casey Eye Institute, Oregon Health Science University, Oregon. Received for publication January 18, 2010; revision received March 22, 2010; accepted August 10, 2010. Reprints: Dr Tarek A. Mohamed, Ophthalmology Department, Assiut University Hospitals, Assiut University Street, Assiut 71515, Egypt (e-mail: [email protected]). Cornea: May 2011 - Volume 30 - Issue 5 - p 550-552 doi: 10.1097/ICO.0b013e3182000ac3 Buy Metrics Abstract Purpose: To assess the incidence of epithelial ingrowth after laser in situ keratomileusis and its correlation with myopic or hyperopic treatment. Methods: This retrospective study analyzed 1000 consecutive LASIK procedures performed by 3 surgeons using identical surgical technique with a Hansatome microkeratome. Eyes that developed epithelial ingrowth were evaluated using the Machat grading system. Patients were subdivided into 2 groups (myopic or hyperopic) based on the preoperative refractive error. Results: The total incidence of epithelial ingrowth was 4.7%. The incidence after primary treatment was 3.9%. The incidence after enhancement was 12.8%. The total incidence of epithelial ingrowth was 3% in the myopic group compared with 23% in the hyperopic group. After primary myopic treatment, there was a 3% incidence of epithelial ingrowth compared with 17% after primary hyperopic treatment. The incidence after enhancement was 7% in the myopic group and 43% in the hyperopic group. Conclusions: Patients undergoing hyperopic laser in situ keratomileusis have a greater incidence of epithelial ingrowth than those undergoing myopic treatment. In addition, enhancement procedures have a higher incidence than primary procedures. Copyright © 2011 Wolters Kluwer Health, Inc. All rights reserved.