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Long-Term Follow-Up of Pterygium Surgery Using a Conjunctival Autograft and Tissucol

Nieuwendaal, Carla P MD; van der Meulen, Ivanka J E MD; Mourits, Maarten MD, PhD; Lapid-Gortzak, Ruthie MD

doi: 10.1097/ICO.0b013e3181dea7f0
Clinical Science

Purpose: To evaluate the rate of recurrence and to detect pre- or postoperative complications in pterygium surgery using fibrin glue to attach the conjunctival autograft.

Methods: Retrospective case series. In a period of 20 months, 35 patients were operated on for a pterygium using a conjunctival autograft, of which 7 patients were operated (20%) for a recurrent pterygium. The autograft was glued with Tissucol Duo 500, a human tissue glue. Follow-up was at least 1 year.

Results: Mean age was 50.4 years (range, 23-80 years), 18 women and 17 men. Success rate was 97.1%. In 1 patient with a primary pterygium, the lesion recurred after 4 months (2.9%). One autograft was lost on the first postoperative day. No other pre- or postoperative problems were encountered.

Conclusions: The use of Tissucol fibrin glue seems to be a safe, easy, and effective technique for attaching the conjunctival autograft in pterygium surgery. The recurrence rate of the procedure is low.

From the Academic Medical Center, Department of Ophthalmology, Amsterdam, The Netherlands.

Received for publication November 27, 2009; revision received February 19, 2010; accepted March 6, 2010.

Reprints: Carla P. Nieuwendaal, Academic Medical Center, Department of Ophthalmology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (e-mail:

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