Penetrating Keratoplasty in Active Acanthamoeba Keratitis : Cornea

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Penetrating Keratoplasty in Active Acanthamoeba Keratitis

Nguyen, Truc H MD; Weisenthal, Robert W MD; Florakis, George J MD; Reidy, James J MD; Gaster, Ronald N MD; Tom, Danita MD

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Cornea 29(9):p 1000-1004, September 2010. | DOI: 10.1097/ICO.0b013e3181cc79a1



To report the results of penetrating keratoplasty (PK) in active Acanthamoeba keratitis (AK).


Nine patients with deep stromal infiltrates because of AK were treated with intensive antiamoebic medical therapy followed by PK during the acute infectious phase because of poor clinical response or poor compliance. Antiamoebic therapy was tapered after PK.


Visual acuity ranged from 20/15 to 20/50 after an average of 17 months after PK with no signs of recurrences. Patients had rapid resolution of symptoms.


PK is a viable option for active AK not responding to maximum medical treatment.

Copyright © 2010 Wolters Kluwer Health, Inc. All rights reserved.

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