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Atypical Mycobacterium Keratitis Associated With Penetrating Keratoplasty: Case Report of Successful Therapy With Topical Gatifloxacin 0.3%

Perez-Balbuena, Ana Lilia MD; Vanzzini-Zago, Virginia ChPB; Garza, Manuel MD; Cancino, Diego Cuevas MD

doi: 10.1097/ICO.0b013e3181b532c7
Case Report

Purpose: To report successful therapy with gatifloxacin 0.3% ophthalmic solution (Zymar) in a patient with atypical mycobacterium keratitis after penetrating keratoplasty.

Methods: A 58-year-old patient was referred for evaluation of microbial keratitis after penetrating keratoplasty.

Results: Clinical examination of the patient revealed an infiltrate at the inferior graft-host junction with a satellite lesion with a mild inflammatory reaction in the anterior chamber. Microbiologic evaluation confirmed the diagnosis of atypical mycobacteria keratitis. The corneal abscess was completely eradicated with a topical course of gatifloxacin 0.3% with preservation of graft clarity and good visual acuity. Topical treatment with gatifloxacin 0.3% was continued for an additional period of 5 months.

Conclusion: Topical gatifloxacin 0.3% may be successfully used to treat microbial keratitis resulting from atypical mycobacteria.

From the *Cornea & Refractive Service; and †Laboratory of Microbiology, Asociación para Evitar la Ceguera en México “Hospital Dr. Luis Sánchez Bulnes,” Mexico.

Received for publication September 1, 2008; revision received May 19, 2009; accepted June 19, 2009.

Reprints: Ana Lilia Pérez-Balbuena, MD, Cornea & Refractive Service, Vicente Garcia Torres, 46 San Lucas Coyoacan, Distrito Federal 04030, Mexico City, Mexico (e-mail:

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