Case ReportDonor-to-Host Transmission of Candida glabrata to Both Recipients of Corneal Transplants From the Same DonorTappeiner, Christoph MD; Goldblum, David MD; Zimmerli, Stefan MD; Fux, Christoph MD; Frueh, Beatrice E MDAuthor Information From the *Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland; †Department of Ophthalmology, Basel University, Basel, Switzerland; and ‡Institute for Infectious Diseases, University of Bern, Bern, Switzerland. Received for publication February 27, 2008; revision received June 12, 2008; accepted June 14, 2008. Conflicts of interest: Zimmerli S: recipient of research grants and member of advisory boards organized by Pfizer AG, Switzerland, Merck-Sharp and Dohme, Switzerland and Fresenius-Kabi, Switzerland. The following authors have no conflicts of interest: Tappeiner C, Goldblum D, Fux C, and Frueh BE. Reprints: Christoph Tappeiner, MD, Department of Ophthalmology, Inselspital, University Hospital, 3010 Bern, Switzerland (e-mail: [email protected]). Cornea: February 2009 - Volume 28 - Issue 2 - p 228-230 doi: 10.1097/ICO.0b013e318183a3e3 Buy Metrics Abstract Purpose: To report 2 cases of exogenous Candida glabrata endophthalmitis after penetrating keratoplasty in recipients of corneas from the same donor transplanted on the same day. Methods: Case reports with ophthalmologic, electron microscopic, and microbiological findings including fungal strain analysis. Results: Two patients developed fungal keratitis and endophthalmitis caused by the same C. glabrata strain within 1 day after penetrating keratoplasty of corneas from the same donor on the same day. Donor-to-host transmission was postulated when eye bank sterility checks were repeatedly negative. Conclusions: A short death-to-harvesting time, routine donor rim cultures, and respecting of a time interval before transplantation may provide an additional safety feature in dealing with corneal tissue from high-risk donors. Copyright © 2009 Wolters Kluwer Health, Inc. All rights reserved.