Case ReportBlueberry Eye: Acquired Total Anterior Staphyloma After a Fungal Corneal UlcerGrieser, Eric J MD; Tuli, Sonal S MD; Chabi, Almira MD; Schultz, Scott MD; Downer, Donald MDAuthor Information From the Department of Ophthalmology, University of Florida, Gainesville, FL. Received for publication February 25, 2008; revision received June 9, 2008; accepted June 16, 2008. Supported by Research to Prevent Blindness. Reprints: Sonal S. Tuli, MD, Department of Ophthalmology, University of Florida, PO Box 100284, 1600 SW Archer Road, Gainesville, FL 32610-0284 (e-mail: [email protected]). Cornea: February 2009 - Volume 28 - Issue 2 - p 231-232 doi: 10.1097/ICO.0b013e318183a3d1 Buy Metrics Abstract Purposes: The purposes of this study were to report the presentation and management of an acquired total anterior staphyloma that resulted from a fungal corneal ulcer and to discuss its pathogenesis. Methods: Observational case report. Clinical observation and surgical intervention of a patient who developed a total anterior staphyloma after a partially treated fungal corneal ulcer. Results: The patient presented with a large traumatic fungal ulcer but was poorly compliant with follow-up and medications. He subsequently presented with a large total anterior staphyloma that resulted from perforation of the ulcer with plugging of the defect with iris and formation of a pseudocornea over the iris. The anterior staphyloma measured 15 × 16 mm and progressed to a stage where the patient was unable to close his eyelids and required a sclerokeratoplasty. Currently, vision is poor from amblyopia and a cloudy graft; however, the eye is intact and comfortable. Conclusions: Anterior staphylomas usually result from untreated fungal ulcers in developing nations. Poor compliance with medications and follow-up was the cause of our patient's anterior staphyloma. Sclerokeratoplasty can restore the globe structurally but has poor visual prognosis. Copyright © 2009 Wolters Kluwer Health, Inc. All rights reserved.