Case ReportOcular Toxicity Caused by Toad VenomLópez-López, José Manuel MD*; Sanabria, María Rosa MD, PhD*†; de Prada, Silvia Jiménez MD‡ Author Information From the *Río Hortega Universitary Hospital, Valladolid, Spain; the †Applied Ophthalmobiology Institute, Valladolid, Spain; and the ‡Medina del Campo Hospital, Valladolid, Spain. Received for publication June 30, 2007; revision received September 7, 2007; accepted September 17, 2007. Reprints: María Rosa Sanabria, IOBA, Facultad de Medicina C/ Ramón y Cajal n° 7, 47005 Valladolid, Spain (e-mail: [email protected]). Cornea 27(2):p 236-237, February 2008. | DOI: 10.1097/ICO.0b013e31815b8317 Buy Metrics Abstract Purpose: To report a case of ocular toxicity caused by toad venom. Methods: Observational case report. Results: A 31-year-old man came to our clinic complaining of burning pain, photophobia, and blurred vision in both eyes. He reported that an hour earlier he had been handling a toad (Bufo bufo). It ejected a liquid from its back that splashed on the patient's face and made him rub his eyes. Corrected visual acuity was 20/50 in the right eye and 20/40 in the left eye. Slit-lamp microscopy revealed mild chemosis and stromal corneal edema with Descemet folds in both eyes. Intraocular pressure (IOP) was 9 mm Hg in both eyes. Posterior segment examination was normal. Topical dexamethasone every 4 hours and cycloplegic 3 times a day were prescribed. Forty-eight hours later, corneal edema and conjunctival chemosis had resolved, and IOP was 18 mm Hg. Conclusions: Ocular toxicity secondary to toad venom may cause corneal edema and low IOP that resolve without specific treatment in a short period. © 2008 Lippincott Williams & Wilkins, Inc.