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Late-onset Interface Inflammation Associated With Wearing Cosmetic Lenses 18 Months After Laser In Situ Keratomileusis

Choi, Hyuck-won MD*; Moon, Sang-Woong MD*; Nam, Kee-Hyun MD; Chung, So-Hyang MD*

doi: 10.1097/ICO.0b013e31815bcd9c
Case Report

Purpose: To report a case of late-onset interface inflammation associated with wearing a cosmetic lens 18 months after laser in situ keratomileusis (LASIK).

Methods: A 25-year-old woman visited our hospital with visual disturbance and ocular pain in the left eye. The patient had undergone LASIK in both eyes 18 months ago and had been wearing cosmetic lenses intermittently for 6 months. The day before presentation, the patient had slept with cosmetic lenses. At presentation, best-corrected visual acuity was 2/200 in the left eye. Slit-lamp examination of the left eye revealed corneal edema and a diffuse granular white infiltrate at the interface.

Results: Intense topical steroid and antibiotic treatment resulted in resolution of interface inflammation. After 2 weeks, the corneal infiltrate had resolved, and best-corrected visual acuity had improved to 20/25.

Conclusions: This case indicates that late-onset interface inflammation can develop in association with the use of cosmetic lenses in LASIK-treated eyes.

From the *Department of Ophthalmology, Inje University College of Medicine, Seoul Paik Hospital, Seoul, Korea; and †Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

Received for publication February 16, 2007; revision received September 5, 2007; accepted September 16, 2007.

Supported by the 2006 Inje University research grant.

Presented in part at the 12th European Society of Cataract and Refractive Surgeons (ESCRS) Winter Refractive Surgery Meeting, February 2, 2007, Athens, Greece.

All authors state that they have no proprietary interest in the products named in this article.

Reprints: So-Hyang Chung, Department of Ophthalmology, Seoul Paik Hospital, Joong-gu, Jeo-dong 2 ga, Seoul, Korea (e-mail:

© 2008 Lippincott Williams & Wilkins, Inc.