Case ReportKeratoglobus in Association With Posterior Polymorphous DystrophyHarissi-Dagher, Mona MD; Dana, M Reza MD, MSc, MPH; Jurkunas, Ula V MD Author Information From the Department of Ophthalmology, Cornea and External Disease Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA. Received for publication May 12, 2007; revision received June 25, 2007; accepted July 16, 2007. Reprints: Ula V. Jurkunas, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114 (e-mail: [email protected]). Cornea: December 2007 - Volume 26 - Issue 10 - p 1288-1291 doi: 10.1097/ICO.0b013e3181557692 Buy Metrics Abstract Purpose: To report a case of a 34-year-old woman presenting with keratoglobus and posterior polymorphous corneal dystrophy (PPMD). Methods: Observational case report including ophthalmologic examination, topographic findings, and specular microscopy findings. Results: This patient presented with corneal steepening on topography consistent with keratoglobus, as well as large areas of irregular polymorphous changes of the corneal endothelium on specular microscopy consistent with PPMD. Conclusions: We report the first case with clinical features of both keratoglobus and PPMD. This report brings forth the description of keratoglobus findings on Orbscan topography. © 2007 Lippincott Williams & Wilkins, Inc.