Institutional members access full text with Ovid®

Share this article on:

Long-Term Outcome in Ocular Intractable Surface Disease With Seoul-Type Keratoprosthesis

Kim, Mee Kum MD*†; Lee, Sang Mok MD*†; Lee, Jae Lim MD; Chung, Tae Young MD*†§; Kim, Young Ha PhD; Wee, Won Ryang MD*†; Lee, Jin Hak MD*†

doi: 10.1097/ICO.0b013e3180415d35
Clinical Science

Purpose: To evaluate the long-term clinical efficacy of the Seoul-type keratoprosthesis (S-KPro).

Methods: S-KPros were implanted into 4 unsighted and 5 sighted eyes in 9 patients: 6 patients were diagnosed with Stevens-Johnson syndrome, 2 had chemical burns, and 1 suffered from ocular pemphigoid. The preoperative visual acuity ranged from light perception to hand motion. The average follow-up period was 62.8 months. We evaluated several clinical factors, including visual acuity, visual field, number of additional grafting procedures, number of capsulotomy procedures, and the interval between retinal detachment and skirt exposure.

Results: The S-KPro showed anatomic success for an average of 62.8 months in 66.7% of the eyes. The average visual acuity preservation time was 31.6 months. Localized glaucomatous visual field defect was not found in any of the sighted patients; however, diffuse visual field constriction was observed after long-term follow-up. Average time of skirt exposure and mean number of additional grafting procedures were 12.9 months and 2.44, respectively. Retinal detachments were developed in all the patients at a mean time interval of 2 months after S-KPro exchange.

Conclusions: S-KPro achieved visual rehabilitation for an average of 31.6 months with long-term anatomic stability in patients with severe intractable ocular surface disease.

From the *Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea; †Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea; ‡Department of Ophthalmology, Valued Eye Clinic, Taejon, Korea; §Department of Ophthalmology, Sungkyunkwan University School of Medicine, Seoul, Korea; and ¶Department of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Korea.

Received for publication June 23, 2006; revision received January 26, 2007; accepted January 30, 2007.

Supported by SNUH Research Fund, Republic of Korea (03-2006-016-0).

Reprints: Jin Hak Lee, Department of Ophthalmology, Seoul National University College of Medicine. #28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea (e-mail:

© 2007 Lippincott Williams & Wilkins, Inc.