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Long-Term Efficacy of Phototherapeutic Keratectomy on Recurrent Corneal Erosion Syndrome

Baryla, J BSc; Pan, Y I MSc; Hodge, W G MD, PhD, FRCSC

doi: 10.1097/01.ico.0000240093.65637.90
Clinical Science

Purpose: To assess the long-term sequelae, principally time-to-first-recurrence, of phototherapeutic keratectomy (PTK) for the treatment of recurrent corneal erosion syndrome (RCES).

Methods: A retrospective case series was performed. Thirty-nine eyes in 33 patients with RCES required PTK and were treated using the VISX STAR Excimer Laser System. The data were analyzed with the Kaplan-Meier survival estimate.

Results: Patients were characterized by the cause of their RCES. More than 50% had epithelial corneal dystrophies, 31% were posttraumatic, and 15% were idiopathic. Overall, 25% of eyes had a recurrence by 3 months, and 36% had a recurrence by 9 months. The mean follow-up time was 17.4 months (range, 0.4-67.6 months). Of those who had a primary recurrence, 38% had a second and 15% had a third. Visual acuity was slightly decreased within 2 weeks after surgery, and 10% of patients developed transient haze. No serious adverse effects were reported.

Conclusion: PTK is an important treatment of RCES refractory to other therapies. Long-term data suggest that most patients treated with PTK do not develop recurrences, and side effects from PTK are minimal.

From the Department of Ophthalmology, The University of Ottawa Eye Institute, Ottawa, Ontario, Canada.

Received for publication October 18, 2005; revision received June 28, 2006; accepted June 30, 2006.

Reprints: William G Hodge, The University of Ottawa Eye Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada (e-mail:

© 2006 Lippincott Williams & Wilkins, Inc.