Case ReportTreatment of Cystic Epithelial Downgrowth With Intralesional Administration of Mitomycin CYu, Carol Shan MBBS (Hons), MRCS (Edin); Chiu, Suk I FRCS, FRCOphth; Tse, Raymond Kwok Kay FRCS, FRCOphthAuthor Information From the Department of Ophthalmology, Caritas Medical Centre, Hong Kong, China. Received for publication September 20, 2004; revision received December 17, 2004; accepted December 18, 2004. Reprints: Carol S. Yu, MBBS, MRCS, Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Cheung Sha Wan, Hong Kong, China (e-mail: [email protected]). Cornea: October 2005 - Volume 24 - Issue 7 - p 884-886 doi: 10.1097/01.ico.0000157410.68148.d6 Buy Metrics Abstract Purpose: To report a case of postoperative cystic epithelial downgrowth treated with needle aspiration and intralesional administration of mitomycin C. Methods: Case report. A 60-year-old woman with a history of right cataract surgery 7 years ago presented with decreased vision of 1/60. The reduced vision was diagnosed secondary to a large acquired cystic epithelial downgrowth on the surface of the iris occluding the pupil. Results: The cystic epithelial downgrowth was treated with aspiration and intralesional administration of mitomycin C solution. There was no evidence of recurrence on follow-up 1 year after the procedure. Conclusions: Treatment of acquired cystic epithelial downgrowth with needle aspiration and intralesional administration of mitomycin C resulted in a satisfactory outcome without undertaking more extensive and invasive surgical treatments. © 2005 Lippincott Williams & Wilkins, Inc.