Case ReportsFungal Keratitis Caused by Colletotrichum gloeosporioidesYamamoto, Noriaki M.D.; Matsumoto, Tadahiko M.D.; Ishibashi, Yasuhisa M.D.Author Information From the Department of Ophthalmology, Gamagori City Hospital, Gamagori (N.Y.); the Department of Dermatology, Toshiba Hospital, Tokyo (T.M.); and the Department of Ophthalmology, Tokyo Women's Medical College Daini Hospital, Tokyo (Y.I.), Japan. Submitted January 9, 2001. Revision received May 25, 2001. Accepted June 1, 2001. Address correspondence and reprint requests to Dr. N. Yamamoto, Department of Ophthalmology, Gamagori City Hospital, 1-1 Mukaida Hirata-cho, Gamagori-shi, Aichi-ken 443-0004, Japan. Cornea: November 2001 - Volume 20 - Issue 8 - p 902-903 Buy Abstract Purpose. To describe a case of fungal keratitis caused by a rare coelomycete pathogen, Colletotrichum gloeosporioides. Methods. An 82-year-old man with myelodysplastic syndrome developed fungal keratitis 6 months after cataract surgery in the left eye. Because the findings of the anterior chamber deteriorated after the initiation of natamycin, additional treatment with topical and systemic fluconazole was initiated. Results. The isolates of corneal scraping grew C. gloeosporioides. After antifungal treatment of 2 months, the corneal lesion resolved with no recurrence of infection over a 5-year follow-up period. Conclusions. A combination treatment of natamycin and fluconazole was effective in the treatment of C. gloeosporioides. © 2001 Lippincott Williams & Wilkins, Inc.