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Photorefractive Keratectomy for Myopia in the Setting of Thygeson's Superficial Punctate Keratitis

Fite, Steven W. M.D.; Chodosh, James M.D.

Case Reports

Purpose. To describe a patient with Thygeson's superficial punctate keratitis who underwent photorefractive keratectomy for the correction of myopia.

Methods. A 49-year-old woman with unilateral Thygeson's keratitis was examined before and after photorefractive keratectomy.

Results. A myopic patient underwent photorefractive keratectomy in the left eye and gained 20/20 uncorrected visual acuity. Seventeen months after surgery, symptomatic Thygeson's keratitis lesions recurred in the peripheral but not the central cornea.

Conclusion. Photorefractive keratectomy reliably corrected myopia in a patient with previous Thygeson's keratitis. The recurrence of lesions only in the peripheral untreated cornea suggests that the inflammatory signal in Thygeson's keratitis may reside in the superficial corneal stroma.

From the Molecular Pathogenesis of Eye Infection Research Center, Dean A. McGee Eye Institute, Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, U.S.A.

Submitted September 26, 2000.

Revision received January 8, 2001.

Accepted January 9, 2001.

Supported in part by an unrestricted grant to the Department of Ophthalmology by Research to Prevent Blindness, New York, New York.

Address correspondence to Dr. J. Chodosh, DMEI-OUHSC, 608 Stanton L. Young Blvd, Oklahoma City, OK 73104, U.S.A. E-mail: james-chodosh@

© 2001 Lippincott Williams & Wilkins, Inc.