Clinical SciencesA Devastating Ocular Pathogen: β-streptococcus Group GRitterband, David C. M.D.; Shah, Mahendra K. M.S.; Buxton, Douglas J. M.D.; Intal, Myrna C. B.S.; Guthrie, Debra S. M.D.; Seedor, John A. M.D.Author Information From the Departments of Ophthalmology (D.C.R., M.K.S., D.J.B., D.S.G., J.A.S.) and Pathology (M.K.S., M.C.I.), The New York Eye and Ear Infirmary, New York, New York, U.S.A.; and New York Medical College, Valhalla, New York, U.S.A. Address correspondence and reprint requests to Dr. D.C. Ritterband, The New York Eye and Ear Infirmary, 310 E. 14th Street, New York, NY 10003, U.S.A. The authors have no proprietary interest in any material or device discussed in this report. Cornea: May 2000 - Volume 19 - Issue 3 - p 297-300 Buy Abstract Purpose. To report the clinical findings, treatment, and outcomes of four cases of β-streptococcus Group G (BHS-G) ocular infection. Methods. The medical and microbiologic records of four cases of BHS-G ocular infection were retrospectively reviewed. Results. Two cases of BHS-G endophthalmitis and two cases of BHS-G keratitis were recorded. Three patients developed fulminant infection within 12 hours of the onset of symptoms. One patient's history was incomplete. One patient developed endophthalmitis from a contaminated donor button; another following cataract surgery. One developed keratitis in a keratoplasty suture tract; and another patient developed a corneal abscess after being struck with a tree branch. The patient with the contaminated donor button developed overwhelming endophthalmitis resulting in no light perception vision, severe pain, and evisceration. The post-operative cataract patient developed a purulent endophthalmitis and is still hypotonus with light perception vision. The second keratitis patient developed a significant suture abscess with marked stromal loss but eventually healed. The traumatic keratitis patient developed a large ulcer with hypopyon and descemetocele but was lost to follow-up. Conclusions. This is the first report of a series of BHS-G ocular infections. The ocular infections were characterized by rapid onset, extreme inflammation, and—despite in vitro antibiotic sensitivity—a poor or sluggish response to antibiotic therapy. © 2000 Lippincott Williams & Wilkins, Inc.