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Opsoclonus

Legend: Video shows a patient with runs of back-to-back saccades in all directions, consistent with opsoclonus. Opsoclonus consists of high-frequency saccadic movements that may be of large amplitude and lack an intersaccadic interval. It localizes to brainstem or cerebellar damage, often resulting from paraneoplastic disease, with or without myoclonus, typically from neuroblastoma in children and small cell lung carcinoma or ovarian cancer in adults.

Duration: 00:26

Associated with: CONTINUUM: Lifelong Learning in Neurology. 25(5):1401-1421, October 2019

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