Continuum: Lifelong Learning in Neurology

Continuum: Lifelong Learning in Neurology® is the official continuing medical education (CME) journal of the American Academy of Neurology (AAN). Published since 1993, Continuum® comprehensive clinical reviews of major neurologic topics for practicing neurologist, residents and fellows, and advanced practice providers. Each bimonthly issue features the latest clinical information related to a single topic area in neurology, offers CME and self-assessment credits, and includes access to Continuum® Audio interviews with the authors.

Mission: Continuum: Lifelong Learning in Neurology aids neurology professionals throughout their careers in improving the clinical care of patients and in demonstrating continued competency.

Vision: Continuum: Lifelong Learning in Neurology will present the highest quality in-depth information on topics in neurology and be the premier continuing medical education publication for neurology professionals throughout their careers.

CME and Self-Assessment

The American Academy of Neurology Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide CME for physicians. For information on Continuum Audio CME, please visit

The American Academy of Neurology Institute designates this enduring material for a maximum of 20 AMA PRA Category 1 Credits™ (for 2018 issues) and 12 AMA PRA Category 1 Credits™ (for 2017 issues and older) upon completion of the Postreading Self-Assessment and CME Test (approved by the American Board of Psychiatry and Neurology as self-assessment, CME [SA-CME] credit toward their Maintenance of Certification Program); and a maximum of 2 AMA PRA Category 1 Credits™ upon completion of the Patient Management Problem. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Per AMA PRA guidelines, only US and licensed international physicians may be awarded AMA PRA Category 1 Credit transcripts. The AAN will issue certificates of participation to non-MD and non-DO health professionals indicating that the activity was designated for AMA PRA Category 1 Credits.

This program is an Accredited Self-Assessment Program (Section 3) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada and approved by the Office of Continuing Medical Education and Professional Development, University of Calgary, on April 1, 2017. Program accreditation expires March 31, 2020. Canadian participants should visit MAINPORT to record learning and outcomes. Canadian participants can claim a maximum of 14 hours for issues from April 2017 to December 2017 and 20 hours for 2018 issues.


The AAN complies with all standards and policies of the ACCME, including identification and resolution of all conflicts of interest prior to the educational activity being delivered to learners. Accordingly, Continuum editors, planners, authors, and editorial staff comply with the AAN's Relationships & Conflicts of Interest Policy​.

Abstracting/Indexing Coverage

Continuum: Lifelong Learning in Neurology is abstracted/indexed in MEDLINE/PubMed (February 2010-present), Embase (June 2006-present), Scopus (2006-present), and PsycInfo (December 2008-present). The National Library of Medicine title abbreviation for MEDLINE, Continuum (Minneap Minn), should be used when citing articles in this journal.

Statement on Peer Review Process

The editor-in-chief, associate editors, and editorial board of Continuum determine topics and review initial manuscripts. Manuscripts on specific issues are solicited from a guest editor who appoints authors to write sections of the issue. Upon receipt of a manuscript from the guest editor, the editor begins the formal review process. It is understood that submissions received are not under consideration by any other journal and that no part of the submission has appeared previously in any but abstract form. Transfer of copyright to the AAN is a condition of publication.

At least two outside peer reviewers anonymous to the authors are selected to assess quality, balance, and clarity of articles and are given appropriate instructions and necessary assessment forms. Critical reviews of the material at other stages of the development process may also be conducted. Upon receipt of final manuscripts, the editor makes the final decision as to whether material is suitable for publication in Continuum.

Informed Consent/Ethics of Experimentation

Authors participating in this AAN education program certify that any work with human or animal subjects reported in their text complies with the guiding principles for experimental procedures endorsed by the AAN. Data presented must comply with ethical guidelines for human and animals research.

Information on Intellectual Property, Permissions, and Reprints

  1. Continuum: Lifelong Learning in Neurology and Continuum are registered trademarks of the AAN and the AAN owns the copyright of the publication.
  2. No part of this publication may be reproduced without written consent from Wolters Kluwer. Permission to reproduce articles for noncommercial and commercial use may be obtained from Rightslink, which can be found at the article level under Request Permission. Alternatively, send an email to​. General information about permissions can be found at Any uses or copies of content from this journal in whole or in part must include the customary full bibliographic citation, including author attribution, date, article title, Continuum online, and the URL and MUST include the copyright notice in the following format: © 2018 American Academy of Neurology.
  3. Personal accounts and/or passwords may not be shared.
  4. Quantity reprints for commercial or academic use may be purchased from Wolters Kluwer. For information and prices, contact


The material presented in Continuum: Lifelong Learning in Neurology has been made available by the AAN for educational purposes only and is not intended to represent the only method or procedure for the medical situations discussed but rather is intended to present an approach, view, statement, or opinion of the author(s), which may be helpful to others who face similar situations.

Opinions expressed by the authors are not necessarily those of the AAN, its affiliates, or the publisher. The AAN, its affiliates, and the publisher disclaim any liability to any party for the accuracy, completeness, efficacy, or availability of the material contained in this publication (including drug dosages) or for any damages arising out of the use or nonuse of any of the material contained in this publication.