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Symptom Management and Lifestyle Modifications in Multiple Sclerosis

Coyle, Patricia K. MD, FAAN

doi: 10.1212/CON.0000000000000325
Review Articles

Purpose of Review: This article reviews the rationale and approach to symptom management and lifestyle modifications in multiple sclerosis (MS).

Recent Findings: MS symptoms are important to treat because they affect quality of life and daily activity. Appreciation of cluster symptoms (where one symptom contributes to another), changes over time, and multimodality therapeutic approaches are guiding optimized symptom management. Equally important are lifestyle modifications that enhance central nervous system reserve and function. These modifications are the foundation for a health maintenance, wellness, and vascular risk factor control program.

Summary: Symptom management and lifestyle modifications are important therapeutic targets to improve the lives of patients with MS.

Address correspondence to Dr Patricia K. Coyle, Department of Neurology, HSC T12-020, State University of New York at Stony Brook, Stony Brook, NY 11794,

Relationship Disclosure: Dr Coyle serves as a consultant for AbbVie Inc; Accordant; Acorda Therapeutics; Bayer AG; Biogen; EMD Serono, Inc; Genentech Inc; Mallinckrodt Pharmaceuticals; Novartis AG; Sanofi Genzyme; and Teva Pharmaceutical Industries Ltd. Dr Coyle receives research support from Actelion Pharmaceuticals Ltd, Genentech/Roche, the National Institute of Neurological Disorders and Stroke, Novartis AG, and Opexa Therapeutics, Inc.

Unlabeled Use of Products/Investigational Use Disclosure: Dr Coyle reports no disclosure.

© 2016 American Academy of Neurology
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