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Neuroradiology in Women of Childbearing Age

Bove, Riley M. MD; Klein, Joshua P. MD, PhD

CONTINUUM: Lifelong Learning in Neurology: February 2014 - Volume 20 - Issue 1 - p 23–41
doi: 10.1212/01.CON.0000443835.10508.2b
Review Articles

Purpose of Review This review summarizes safety concerns associated with diagnostic neuroimaging in patients who are of childbearing age, focusing on diagnostic modalities and radiologic features of neurologic conditions encountered by pregnant women.

Recent Findings During pregnancy, women experience a range of physiologic changes that can affect neurologic function. These include endocrine, hemodynamic, endothelial, immunologic, and coagulopathic changes that can alter susceptibility to stroke, subarachnoid hemorrhage, demyelination, venous thrombosis, and other neurologic conditions. Unique safety concerns are associated with imaging procedures performed to diagnose neurologic conditions that occur during pregnancy.

Summary This review discusses the use of diagnostic neuroimaging, including administration of IV contrast, in pregnant women and in nonpregnant women of childbearing age.

Address correspondence to Dr Joshua P. Klein, Department of Neurology, Room AB-124, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115,

Relationship Disclosure: Dr Bove reports no disclosure. Dr Klein receives financial compensation for serving on the editorial boards of the Journal of Neuroimaging and AccessMedicine Neurology, and royalties from McGraw-Hill for Adams and Victor’s Principles of Neurology.

Unlabeled Use of Products/Investigational Use Disclosure: Drs Bove and Klein report no disclosures.

© 2014 American Academy of Neurology
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