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Wirrell, Elaine; Nickels, Katherine, C.

CONTINUUM: Lifelong Learning in Neurology: June 2010 - Volume 16 - Issue 3, Epilepsy - p 57-85
doi: 10.1212/01.CON.0000368232.19116.3d

Epilepsy syndromes denote specific constellations of clinical seizure type(s), EEG findings, and other characteristic clinical features. Most syndromes recognized in epilepsy are genetic and developmental disorders that begin in the pediatric years. Epilepsy syndromes are divided into idiopathic (primary) types, in which the presumed etiology is genetic, versus symptomatic (secondary) types, in which there is either an underlying etiology that is known or presumed based on other evidence of brain dysfunction. Epilepsies are also classified by those with generalized seizures and those with localization-related seizures. Identification of a specific syndrome is important to define the best treatment and accurately prognosticate long-term outcome for children with epilepsy. In this chapter, clinical and electrographic features as well as inheritance patterns of common pediatric epilepsy syndromes are discussed.

Relationship Disclosure: Drs Wirrell and Nickels have nothing to disclose.

Unlabeled Use of Products/Investigational Use Disclosure: Drs Wirrell and Nickels discuss the use of stiripentol and clobazam, which are not routinely available in the United States for treatment of epilepsy.

© 2010 American Academy of Neurology
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